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5S Langouët

 

Summary for 2001 [at-glance overview of S Langouët work for the selected year as suggested by data mining algorithms]

This is an Authoratory overview of author S Langouët. According to available data, in 2001 S Langouët published at least 5 articles. This work was completed in collaboration with several authors including Guillouzo, A and Guengerich, F P. Several other authors have collaborated with S Langouët as well. There is no information about the funding or the grants awarded to support this work.

S Langouët has rank 8 when compared to all other authors using the keyword Quinoxalines. Analysis of the article abstracts and the titles suggests that S Langouët professional interests are focused around "8-dimethylimidazo 5-f quinoxaline", "2-amino-3 8-dimethylimidazo 5-f" and "5-f quinoxaline human". These might also be referred to as "quinoxaline human", "8-dimethylimidazo 5-f" or "2-amino-3 8-dimethylimidazo". Statistical analysis shows that S Langouët's writing is likely to contains terms "human", "cells", "5-f", "quinoxaline", "liver" and "p450".

Unfortunately, there is not enough information to establish S Langouët affiliation. Luckily, several email addresses are on file.

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Alternative names (1) [other authors with names similar to S Langouët]

Year 2001 Charts [S Langouët frequent coauthors and the most common unique vocabulary terms for the selected year]

Historical Performance Charts [graphical overview of S Langouët publication and funding history for the range of years]

Emails (2) [email addresses extracted from S Langouët affiliations]

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S Langouët Coauthors (8) [all coauthors with the number of joint publications]

4

13Guillouzo, A

3

35Guengerich, F P

3

8Turesky, R J

2

13Fay, L B

1

9Fardel, O

1

7Courtois, A

1

7Payen, L

1

3Salles, B

 

Affiliations (5) [condensed summary of the S Langouët affiliations, the leading number and the color conveys importance]

  • 1Nestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland.
    1INSERM U456, Faculté de Pharmacie, Université de Rennes I, 35043 Rennes, France.
    1INSERM U456, Détoxication et Réparation Tissulaire, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Rennes I, France.
    1INSERM U456, Detoxication et Reparation Tissulaire, Faculté de Pharmacie, 2 Avenue du Pr L. Bernard, 35043 Rennes Cedex, France.
    1INSERM U456, Faculté de Pharmacie, Rennes, France.

Key Opinion Leader In [S Langouët is considered a key opinion leader in any keyword where the rank of 5 is achieved, the leading number before the keyword shows the author's rank as compared to all other authors]

  • 8Quinoxalines | 11Cytochrome P-450 CYP1A2 | 34Mutagens | 80Hepatocytes

Keywords (32) [keywords assigned to S Langouët articles by PubMed, the leading number and the color conveys importance]

  • 4Hepatocytes | 4Rats | 4Humans | 4Animals | 3Mutagens | 3Cells, Cultured | 3Cytochrome P-450 CYP1A2 | 3Quinoxalines | 2Microsomes, Liver | 2DNA Adducts | 2Biotransformation | 2Theophylline | 2Metabolic Detoxication, Drug | 2Enzyme Inhibitors | 2Tumor Cells, Cultured | 1Amines | 1Rats, Wistar | 1Antineoplastic Agents | 1NADPH-Ferrihemoprotein Reductase | 1Cell Separation | 1Polycyclic Hydrocarbons, Aromatic | 1Cell-Free System | 1Oxidation-Reduction | 1Methylcholanthrene | 1Species Specificity | 19,10-Dimethyl-1,2-benzanthracene | 1P-Glycoprotein | 1Magnetic Resonance Spectroscopy | 1Benzopyrenes | 1Substrate Specificity | 1Male | 1ATP-Binding Cassette Transporters

S Langouët Unique Vocabulary (96) [single words, word pairs and phrases obtained by analysis of abstracts and titles, the leading number and the color conveys importance; S Langouët might be a good expert witness on these terms]

  • 8human | 8cells | 75-f | 7quinoxaline | 6liver | 6p450 | 58-dimethylimidazo | 5metabolism | 52-amino-3 | 51a2 | 5rat | 4pathway | 4differences | 4resistance | 4meiqx | 3major | 3transporters | 3activity | 3hepatocytes | 3multidrug | 3pah | 2risk | 2microsomes | 2quinoxaline-8-carboxylic | 2efflux | 2assessing | 2display | 2unaltered | 2mutagen | 2biological | 2may | 2health
  • 5quinoxaline human | 58-dimethylimidazo 5-f | 52-amino-3 8-dimethylimidazo | 55-f quinoxaline | 5p450 1a2 | 4liver cells | 4rat liver | 3multidrug resistance | 3human hepatocytes | 3human rat | 3resistance transporters | 2expression multidrug | 2differences n-oxidation | 2detoxification pathway | 2considered assessing | 2polycyclic aromatic | 25-f quinoxaline-8-carboxylic | 2health risk | 2cytochromes p450 | 22-amino-3-methylimidazo 5-f | 2n-oxidation 2-amino-3 | 21a2 quinoxaline | 2hydrocarbon-resistant rat | 2unaltered expression | 2assessing human | 2cytochrome p450 | 2catalyzed cytochrome | 2hepatocytes 2-amino-3-methylimidazo | 2affect biological | 2transporters polycyclic | 2liver microsomes | 2aromatic hydrocarbon-resistant
  • 58-dimethylimidazo 5-f quinoxaline | 52-amino-3 8-dimethylimidazo 5-f | 55-f quinoxaline human | 3multidrug resistance transporters | 3quinoxaline human hepatocytes | 2considered assessing human | 2must considered assessing | 2metabolism 2-amino-3 8-dimethylimidazo | 2differences n-oxidation 2-amino-3 | 2quinoxaline-8-carboxylic acid major | 2aromatic hydrocarbon-resistant rat | 2hepatocytes 2-amino-3-methylimidazo 5-f | 2human rat liver | 2acid major detoxification | 2cytochrome p450 1a2 | 2n-oxidation 2-amino-3 8-dimethylimidazo | 2unaltered expression multidrug | 2regioselective differences n-oxidation | 2transporters polycyclic aromatic | 2hydrocarbon-resistant rat liver | 2resistance transporters polycyclic | 2pathway catalyzed cytochrome | 2polycyclic aromatic hydrocarbon-resistant | 2detoxification pathway catalyzed | 2expression multidrug resistance | 2affect biological activity | 2rat liver microsomes | 25-f quinoxaline-8-carboxylic acid | 2cytochromes p450 1a2 | 2assessing human health | 2liver microsomes cytochromes | 2human hepatocytes 2-amino-3-methylimidazo

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Funding (0) [selected NIH grants to S Langouët and the award amounts for recent years]

  • award information is not available

S Langouët Articles (5) [selected PubMed articles for the year 2001 with the links to a full text at PubMed]

  • Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2. (2001) >>

    Nestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland.

    2Huynh-Ba, T, 1Parisod, V, 5Langouët, S, 8Turesky, R J, 35Guengerich, F P.

  • Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2. (2001) >>

    INSERM U456, Faculté de Pharmacie, Université de Rennes I, 35043 Rennes, France.

    3Markovic, J, 2Huynh-Ba, T, 13Guillouzo, A, 5Welti, D H, 2Kerriguy, N, 5Langouët, S, 8Turesky, R J, 35Guengerich, F P, 13Fay, L B.

  • Determination of nucleotide excision repair capacity of liver cells in vivo and in vitro by a cell-free assay. (2001) >>

    INSERM U456, Détoxication et Réparation Tissulaire, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Rennes I, France.

    1Fautrel, A, 13Guillouzo, A, 1Sparfel, L, 3Salles, B, 5Langouët, S.

  • Unaltered expression of multidrug resistance transporters in polycyclic aromatic hydrocarbon-resistant rat liver cells. (2001) >>

    INSERM U456, Detoxication et Reparation Tissulaire, Faculté de Pharmacie, 2 Avenue du Pr L. Bernard, 35043 Rennes Cedex, France.

    7Courtois, A, 9Fardel, O, 7Payen, L, 13Guillouzo, A, 5Langouët, S.

  • Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes. (2001) >>

    INSERM U456, Faculté de Pharmacie, Rennes, France.

    13Guillouzo, A, 5Welti, D H, 2Kerriguy, N, 5Langouët, S, 8Turesky, R J, 35Guengerich, F P, 13Fay, L B.