₄₁Richard A Flavell

Richard A Flavell Articles (41) [selected PubMed articles for the year 2003 with the links to a full text at PubMed]

• Too much data, only first 100 publications and/or coauthors will be displayed. Unabridged data can only be viewed as XML or CSV documents.

• A critical role of neural-specific JNK3 for ischemic apoptosis. (2003) >>

  Department of Pediatrics, Division of Developmental Biology, Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

  ₅Yang, Derek D, ₆Rakic, Pasko, ₃Whitmarsh, Alan J, ₄₁Flavell, Richard A, ₁Schloemer, Aryn J, ₁Liao, Guanghong, ₇Haddad, Gabriel G, ₁₀Dong, Chen, ₁Bao, Jue, ₂Banasiak, Kenneth J, ₂₁Davis, Roger J, ₃Kuan, Chia-Yi.

• Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. (2003) >>

  The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

  ₅Hoebe, Kasper, ₁₄Han, Jiahuai, ₄₁Flavell, Richard A, ₁₂Beutler, Bruce, ₂Janssen, Edith M, ₃Kim, Sung O, ₂Alexopoulou, Lena.

• A Salmonella protein causes macrophage cell death by inducing autophagy. (2003) >>

  Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.

  ₂Hernandez, Lorraine D, ₄₁Flavell, Richard A, ₆Galán, Jorge E, ₁₁Pypaert, Marc.

• The Ro autoantigen binds misfolded U2 small nuclear RNAs and assists mammalian cell survival after UV irradiation. (2003) >>

  Department of Cell Biology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06536, USA.

  ₅Yang, Derek D, ₃Wolin, Sandra L, ₅Shi, Hong, ₄₁Flavell, Richard A, ₃Chen, Xinguo, ₃Smith, James D.

• STAT3 is required for Flt3L-dependent dendritic cell differentiation. (2003) >>

  Section of Immunobiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₇Fu, Xin-Yuan, ₄₁Flavell, Richard A, ₂Welte, Thomas, ₁Laouar, Yasmina.

• MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury. (2003) >>

  Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

  ₁Choi, Augustine M, ₁Fearns, Colleen, ₃Otterbein, Sherrie L, ₃Ulevitch, Richard J, ₁₄Otterbein, Leo E, ₄₁Flavell, Richard A, ₁Ifedigbo, Emeka, ₁Knickelbein, Roy, ₃₄Liu, Fang, ₁Morse, Danielle E.

• Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. (2003) >>

  Section of Immunobiology, Howard Hughes Medical Institute, New Haven, CT 06520, USA.

  ₁Xiao, Changchun, ₅Wrana, Jeffrey L, ₁Shim, Jae-Hyuck, ₇Fu, Xin-Yuan, ₄₁Flavell, Richard A, ₁₀Dong, Chen, ₃Zhang, Samuel Shao-min, ₇Ghosh, Sankar, ₁Klüppel, Michael, ₇Hogan, Brigid L M.

• Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. (2003) >>

  Dept. of Pathology, Yale University School of Medicine, P.O. Box 208023, New Haven, CT 06520, USA.

  ₁Jacoby, Joerg, ₂Chai, Gui-Xuan, ₃Gao, Qian, ₁Hansen, William, ₇Fu, Xin-Yuan, ₄₁Flavell, Richard A, ₈Iwamoto, Yoshiki, ₁Wolfgang, Michael J, ₉Pober, Jordan S, ₃Kano, Arihiro.

• Caspase regulation of genotoxin-induced neural precursor cell death. (2003) >>

  Division of Neuropathology, Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.

  ₁Klocke, Barbara J, ₃Cecconi, Francesco, ₂₄Korsmeyer, Stanley J, ₄Roth, Kevin A, ₁Lindsten, Tulia, ₄₁Flavell, Richard A, ₂₀Thompson, Craig B, ₁D'Sa, Cleta.

• Disruption of TGF-beta signaling in T cells accelerates atherosclerosis. (2003) >>

  Center for Molecular Medicine, L8:03 Karolinska Hospital, SE-17176 Stockholm, Sweden.

  ₃Zhou, Xinghua, ₄₁Flavell, Richard A, ₇Rudling, Mats, ₄Gorelik, Leonid, ₈Hansson, Göran K, ₁Robertson, Anna-Karin L.

• Phosphatidylserine receptor is required for clearance of apoptotic cells. (2003) >>

  Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₁Sarkisian, Matthew R, ₂Mehal, Wajahat Z, ₆Rakic, Pasko, ₄₁Flavell, Richard A, ₁Li, Ming O.

• CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. (2003) >>

  Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Cambridge University, United Kingdom.

  ₄₁Flavell, Richard A, ₁Tran, Elise H, ₄Gorelik, Leonid, ₁McGregor, Catrin M, ₃Green, E Allison.

• Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. (2003) >>

  Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

  ₁Pischke, Soeren E, ₅Zhou, Zhihong, ₃Otterbein, Sherrie L, ₂Loop, Torsten, ₁₄Otterbein, Leo E, ₄₁Flavell, Richard A, ₁₆Choi, Augustine M K, ₄Morse, Danielle, ₂₁Davis, Roger J.

• Mechanism of p38 MAP kinase activation in vivo. (2003) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

  ₁Jaeschke, Anja, ₁Brancho, Deborah, ₁Takeshita, Toshikazu, ₂Kelkar, Nyaya, ₅Ventura, Juan-Jose, ₁₃Tanaka, Yoshinori, ₄₁Flavell, Richard A, ₂₀Tanaka, Nobuyuki, ₂₁Davis, Roger J, ₁Kyuuma, Masanao.

• Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). (2003) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.

  ₃Sheppard, Barbara J, ₁Delmotte, Marie-Hélène, ₂Kelkar, Nyaya, ₄₁Flavell, Richard A, ₃Weston, Claire R, ₁Barrett, Tamera, ₂₁Davis, Roger J.

• Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice. (2003) >>

  Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06510, USA.

  ₄Miyake, Katsuya, ₁Chakrabarti, Sabyasachi, ₁Fowler, Kimberly T, ₂Kobayashi, Koichi S, ₄₁Flavell, Richard A, ₃Liston, David R, ₃Andrews, Norma W, ₂Marks, Carolyn B, ₄Gorelick, Fred S.

• Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia. (2003) >>

  Department of Cardiology, Guy's, King's and St Thomas' School of Medicine, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.

  ₁Heads, Richard J, ₄₁Flavell, Richard A, ₄Tanno, Masaya, ₄Marber, Michael S, ₁₃Jiang, Jie, ₁Saurin, Adrian T, ₃Martin, Jody L, ₂₁Davis, Roger J, ₂Bassi, Rekha, ₃Gorog, Diana A.

• CD154-CD40-independent up-regulation of B7-2 on splenic antigen-presenting cells and efficient T cell priming by staphylococcal enterotoxin A. (2003) >>

  Section of Immunobiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₄₁Flavell, Richard A, ₃Eshima, Koji, ₈Choi, Yongwon.

• Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice. (2003) >>

  Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

  ₅Zhou, Zhihong, ₁₄Otterbein, Leo E, ₄₁Flavell, Richard A, ₁₆Choi, Augustine M K, ₄Morse, Danielle, ₇Watkins, Simon, ₂₁Davis, Roger J, ₆Alber, Sean.

• Intracellular debugging. (2003) >>

  ₁Eynon, Elizabeth E, ₂Kobayashi, Koichi S, ₄₁Flavell, Richard A.

• Regulation of the Th2 cytokine locus by a locus control region. (2003) >>

  Section of Immunobiology, Yale University School of Medicine, Yale University, New Haven, CT 06520, USA.

  ₁Griffin, Thomas J, ₄₁Flavell, Richard A, ₂Fields, Patrick E, ₁Lee, Gap Ryol.

• Caspases and T lymphocytes: a flip of the coin? (2003) >>

  Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.

  ₄₁Flavell, Richard A, ₁Lakhani, Saquib.

• Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury. (2003) >>

  Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.

  ₄Zhang, Xuchen, ₃Shan, Peiying, ₄₁Flavell, Richard A, ₆Alam, Jawed, ₅Lee, Patty J, ₂₁Davis, Roger J.

• JunD mediates survival signaling by the JNK signal transduction pathway. (2003) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, Department of Biochemistry & Molecular Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

  ₅Ventura, Juan-Jose, ₄₁Flavell, Richard A, ₁Hess, Patricia, ₂Lamb, Jennifer A, ₂₁Davis, Roger J.

• Transcriptional regulation of th2 differentiation by inducible costimulator. (2003) >>

  Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195, USA.

  ₅Nurieva, Roza I, ₂Duong, Julie, ₆Dianzani, Umberto, ₁Kishikawa, Hiroko, ₁Ho, I cheng, ₄₁Flavell, Richard A, ₂Rojo, José M, ₁₀Dong, Chen.

• A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen. (2003) >>

  Department of Cell Biology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06536, USA.

  ₅Yang, Derek D, ₁Eynon, Elizabeth, ₃Wolin, Sandra L, ₅Shi, Hong, ₄₁Flavell, Richard A, ₂Noe, Dennis A, ₅Brash, Douglas E, ₁Xue, Dahai, ₃Chen, Xinguo, ₂Cedervall, Tommy, ₃Smith, James D, ₇Kashgarian, Michael.

• JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. (2003) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

  ₄Wong, Anthony, ₄₁Flavell, Richard A, ₃Weston, Claire R, ₃Goad, Mary E P, ₂₁Davis, Roger J, ₂Hall, J Perry.

• TNF-alpha impairs peripheral tolerance towards beta-cells, and local costimulation by B7.1 enhances the effector function of diabetogenic T cells. (2003) >>

  Department of Diabetes Autoimmunity, Hagedorn Research Institute, Gentofte, Denmark.

  ₁Picarella, Dominic E, ₃Guerder, Sylvie, ₃Michelsen, Birgitte K, ₄₁Flavell, Richard A, ₂Skak, Kresten, ₁Brenden, Nina.

• c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor. (2003) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

  ₅Ventura, Juan-Jose, ₄₁Flavell, Richard A, ₂Lamb, Jennifer A, ₃Kennedy, Norman J, ₂₁Davis, Roger J.

• Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. (2003) >>

  Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

  ₁Chupp, Geoffrey L, ₄Zhang, Xuchen, ₃Shan, Peiying, ₁Sasidhar, Madhu, ₄₁Flavell, Richard A, ₅Lee, Patty J, ₁₆Choi, Augustine M K.

• A pool of central memory-like CD4 T cells contains effector memory precursors. (2003) >>

  Section of Immunobiology, Yale University School of Medicine and Howard Hughes Medical Institute, New Haven, CT 06520, USA.

  ₁₂Bottomly, Kim, ₄₁Flavell, Richard A, ₂Blander, J Magarian, ₁Metz, Daniela, ₅Janeway, Charles A, ₁Kim, Sang-Won, ₂Sant'Angelo, Derek B.

• A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse. (2003) >>

  Section of Immunobiology and Howard Hughes Medical Institute, Yale University School of Medicine, PO Box 208011, New Haven, CT 06520-8011, USA.

  ₃Grewal, Iqbal S, ₃Wong, F Susan, ₄₁Flavell, Richard A, ₁Mora, Conchi, ₃Eshima, Koji, ₃Green, E Allison.

• Inducible costimulator is essential for collagen-induced arthritis. (2003) >>

  Department of Immunology, and. Department of Comparative Medicine, University of Washington School of Medicine, Seattle, Washington, USA.

  ₅Nurieva, Roza I, ₂Duong, Julie, ₂Treuting, Piper, ₄₁Flavell, Richard A, ₁₀Dong, Chen.

• The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight. (2003) >>

  Department of Medicine, Yale University School of Medicine, New Haven, CT 06520-8029, USA.

  ₂Li, YanYan, ₂Desir, Gary V, ₁Li, Guoyong, ₁Xu, Jianchao, ₄₁Flavell, Richard A, ₂Kaczmarek, Leonard, ₁Wu, Yanling, ₁Wang, Peili, ₅Koni, Pandelakis A.

• Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. (2003) >>

  Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

  ₄₁Flavell, Richard A, ₂Sluss, Hayla K, ₆Bar-Sagi, Dafna, ₃Kennedy, Norman J, ₆Jones, Stephen N, ₂₁Davis, Roger J.

• STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. (2003) >>

  Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₄₁Flavell, Richard A, ₃Wang, Tian, ₂Hesslein, David G T, ₁₀Fikrig, Erol, ₂Welte, Thomas, ₃Yin, Zhinan, ₇Bothwell, Alfred L M, ₅Zhang, Zhiyuan, ₁₂Li, En, ₂Craft, Joseph E, ₇Fu, Xin-Yuan, ₈Iwamoto, Yoshiki, ₁Zhang, Samuel S M, ₃Kano, Arihiro, ₅Koni, Pandelakis A.

• Prostaglandin F2alpha- and FAS-activating antibody-induced regression of the corpus luteum involves caspase-8 and is defective in caspase-3 deficient mice. (2003) >>

  Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.

  ₁Matikainen, Tiina, ₅Tilly, Jonathan L, ₃Lynch, Maureen P, ₅Rueda, Bo R, ₄₁Flavell, Richard A, ₁Carambula, Silvia F, ₁Gonçalves, Paulo Bayard D, ₃Pru, James K.

• Accelerated diabetes in rat insulin promoter-tumor necrosis factor-alpha transgenic nonobese diabetic mice lacking major histocompatibility class II molecules. (2003) >>

  Department of Immunology, Mayo Clinic, Rochester, Minnesota 55905, USA.

  ₄₁Flavell, Richard A, ₁₁David, Chella S, ₂Rajagopalan, Govindarajan, ₆Kudva, Yogish C.

• Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo. (2003) >>

  Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.

  ₃Kolesnick, Richard N, ₅Sherr, David H, ₁Perez, Gloria I, ₂Canning, Jacqueline, ₅Tilly, Jonathan L, ₂₄Korsmeyer, Stanley J, ₄₁Flavell, Richard A, ₄Schlezinger, Jennifer J, ₂Takai, Yasushi, ₃Pru, James K, ₈Yuan, Junying.

• Contribution of Fas to diabetes development. (2003) >>

  The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

  ₁Tcherepanov, Andrew, ₄₁Flavell, Richard A, ₂Savinov, Alexei Y, ₃Chervonsky, Alexander V, ₃Green, E Allison.

• Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. (2003) >>

  Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

  ₄Zhang, Xuchen, ₃Shan, Peiying, ₁₄Otterbein, Leo E, ₄₁Flavell, Richard A, ₆Alam, Jawed, ₅Lee, Patty J, ₁₆Choi, Augustine M K, ₂₁Davis, Roger J.