₄₂Frank J Gonzalez

Frank J Gonzalez Articles (42) [selected PubMed articles for the year 2003 with the links to a full text at PubMed]

• Too much data, only first 100 publications and/or coauthors will be displayed. Unabridged data can only be viewed as XML or CSV documents.

• Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function. (2003) >>

  Department of Social and Environmental Medicine H3, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

  ₃Inoue, Shintaro, ₃Horie, Kyoji, ₄₂Gonzalez, Frank J, ₉Hosokawa, Ko, ₄Kondoh, Gen, ₁₀Takeda, Junji, ₄Sano, Shigetoshi, ₁Tojo, Hiromasa, ₅Takagi, Satoshi, ₇Hara, Mariko, ₃Tomita, Shuhei, ₁₆Itami, Satoshi.

• Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. (2003) >>

  Laboratory of Metabolism, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₄₂Gonzalez, Frank J, ₁₀Kliewer, Steven A, ₄Sinal, Christopher J, ₁₀Brewer, H Bryan, ₃Guo, Grace L, ₁₀Ward, Jerrold M, ₄Lambert, Gilles, ₁₇Negishi, Masahiko.

• Role of gene knockout and transgenic mice in the study of xenobiotic metabolism. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20814, USA.

  ₄₂Gonzalez, Frank J.

• Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice. (2003) >>

  Laboratory of Metabolism, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.

  ₄₂Gonzalez, Frank J, ₄Cheung, Connie, ₅Akiyama, Taro E, ₁Kudo, Gen.

• T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. (2003) >>

  Department of Biochemistry, Kagawa Medical University, Kagawa, Japan.

  ₅Takahama, Yousuke, ₁Maekawa, Shin-ichi, ₁Tohi, Keiko, ₄₂Gonzalez, Frank J, ₂Miyatake, Akira, ₁₀Takeda, Junji, ₁Jiang, Hou-Bo, ₅Furukawa, Aizo, ₅Takagi, Satoshi, ₃Tomita, Shuhei, ₁Ichikawa, Yoshiyuki, ₂Ueno, Tomoo.

• Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. (2003) >>

  Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

  ₁Eisenman, Daniel, ₈Kulkarni, Rohit N, ₄₂Gonzalez, Frank J, ₄Sarraf, Pasha, ₁₃Spiegelman, Bruce M, ₁₂Magnuson, Mark A, ₂Okada, Terumasa, ₁Hsu, Chung-Hsin, ₂₅Kahn, C Ronald, ₃Rosen, Evan D, ₂Ozcan, Umut.

• Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine. (2003) >>

  Division of Gastroenterology and Hepatology, Department of Medicine, Karl-Franzens University, Auenbruggerplatz 15, A-8036 Graz, Austria.

  ₁₁Trauner, Michael, ₅Zatloukal, Kurt, ₁Arbeiter, Silvia, ₄₂Gonzalez, Frank J, ₁₈Wagner, Martin, ₄Fuchsbichler, Andrea, ₅Fickert, Peter, ₃Marschall, Hanns-Ulrich, ₃Silbert, Dagmar, ₇Denk, Helmut, ₄Zollner, Gernot.

• Defective brain development in mice lacking the Hif-1alpha gene in neural cells. (2003) >>

  Department of Immune System Development, RIKEN Research Center for Allergy and Immunology, Tokushima 770-8503, Japan.

  ₅Takahama, Yousuke, ₆Sakamoto, Masami, ₂Ueda, Natsuo, ₄₂Gonzalez, Frank J, ₂Sakamoto, Haruhiko, ₁Kitahama, Yuki, ₅Ueno, Masaki, ₁Ueki, Masaaki, ₈Kageyama, Ryoichiro, ₃Tomita, Shuhei, ₂Maekawa, Nobuhiro, ₁₃Gassmann, Max.

• Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. (2003) >>

  Department of Medicine, Karl-Franzens University, Graz, Austria.

  ₁₁Trauner, Michael, ₁₈Wagner, Martin, ₄₂Gonzalez, Frank J, ₅Fickert, Peter, ₃Marschall, Hanns-Ulrich, ₃Silbert, Dagmar, ₆Schuetz, John D, ₇Denk, Helmut, ₅Zatloukal, Kurt, ₄Fuchsbichler, Andrea, ₃Guo, Grace L, ₄Zollner, Gernot, ₃Tsybrovskyy, Oleksiy.

• Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. (2003) >>

  Diabetes Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₃Johnson, Lisa, ₄₂Gonzalez, Frank J, ₁₂Vinson, Charles, ₈Haluzik, Martin, ₂Dietz, Kelly R, ₅Reitman, Marc L, ₇Gavrilova, Oksana, ₃Matsusue, Kimihiko, ₂Cutson, Jaime J, ₂Nicol, Christopher J.

• Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. (2003) >>

  Research Division, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02215, USA.

  ₄₂Gonzalez, Frank J, ₁₃Spiegelman, Bruce M, ₁Jozsi, Alison C, ₄Ristow, Michael, ₅Goodyear, Laurie J, ₂₅Kahn, C Ronald, ₃Norris, Andrew W, ₅Chen, Lihong, ₁Szanto, Ildiko, ₃Fisher, Simon J, ₃Rosen, Evan D, ₄Hirshman, Michael F.

• Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression. (2003) >>

  UR545 INSERM, Département d'Athérosclérose, Institut Pasteur de Lille, Lille, France.

  ₁₀Barbier, Olivier, ₄₂Gonzalez, Frank J, ₅Kosykh, Vladimir, ₃₁Staels, Bart, ₂₁Fruchart, Jean-Charles, ₃Claudel, Thierry, ₄Durán-Sandoval, Daniel, ₁₅Inoue, Yusuke, ₁Fruchart, Jamila.

• Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones. (2003) >>

  LAboratory of Molecular Carcinogenesis, National Cancer Institute, National Institutes of Healh, Bethesda, Maryland, USA.

  ₄₂Gonzalez, Frank J, ₁Gelboin, Harry L, ₁Li, Jianqi, ₁Krausz, Kristopher, ₇₅Chen, Jun, ₁Ge, Xia, ₁₀Hu, Ming.

• Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice. (2003) >>

  Department of Veterinary Science, Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, 226 Fenske Laboratory, University Park, PA 16802, USA.

  ₄₂Gonzalez, Frank J, ₁Burns, Amanda M, ₂Aoyama, Toshifumi, ₃Peters, Jeffrey M.

• Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₂Kamiya, Akihide, ₄₂Gonzalez, Frank J, ₁₅Inoue, Yusuke.

• Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₄Idle, Jeffrey R, ₄₂Gonzalez, Frank J, ₃Herraiz, Tomas, ₄Küpfer, Adrian, ₅Yu, Ai-ming.

• Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity. (2003) >>

  Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.

  ₅Miyata, Masaaki, ₄₂Gonzalez, Frank J, ₄Sinal, Christopher J, ₄Nagata, Kiyoshi, ₂Nakamura, Toshifumi, ₁Kitada, Hirotaka, ₃Guo, Grace L, ₁Honma, Wataru, ₁Tozawa, Aki, ₄Yamazoe, Yasushi, ₁Shimada, Miki.

• Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles. (2003) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

  ₄₂Gonzalez, Frank J, ₆Kimura, Shioko, ₁Dragan, Yvonne, ₁Yim, Sun Hee, ₁₀Ward, Jerrold M, ₂Scacheri, Peter C, ₆Yamada, Atsushi.

• In vivo stabilization of nuclear retinoid X receptor alpha in the presence of peroxisome proliferator-activated receptor alpha. (2003) >>

  Department of Aging Biochemistry, Research Center on Aging and Adaptation, Shinshu University School of Medicine, 3-1-1 Asahi, 390-8621, Matsumoto, Japan.

  ₃Kamijo, Yuji, ₄₂Gonzalez, Frank J, ₅Hora, Kazuhiko, ₃Tanaka, Naoki, ₁₈Kiyosawa, Kendo, ₂Aoyama, Toshifumi, ₂Makishima, Hideki.

• PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. (2003) >>

  Department of Cellular and Molecular Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla 92093-0651, USA.

  ₄₂Gonzalez, Frank J, ₆Glass, Christopher K, ₅Akiyama, Taro E, ₂Welch, John S, ₁Ricote, Mercedes.

• Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₃Feigenbaum, Lionel, ₄₂Gonzalez, Frank J, ₂Granvil, Camille P, ₄Cheung, Connie, ₂Elizondo, Guillermo, ₅Krausz, Kristopher W, ₅Akiyama, Taro E, ₅Yu, Ai-ming.

• Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. (2003) >>

  Mount Sinai School of Medicine, New York, New York 10029, USA.

  ₄₂Gonzalez, Frank J, ₄Sinal, Christopher J, ₁Breslow, Jan, ₈Ma, Lin, ₆Sehayek, Ephraim, ₄Chen, Frank, ₂Ananthanarayanan, M, ₅Shneider, Benjamin L, ₅Dawson, Paul A.

• Genetics and susceptibility to toxic chemicals: do you (or should you) know your genetic profile? (2003) >>

  Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, Michigan 48201, USA.

  ₂Zacharewski, Timothy R, ₄₂Gonzalez, Frank J, ₄Lash, Lawrence H, ₁₁Hines, Ronald N, ₂Rothstein, Mark A.

• Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes. (2003) >>

  Duke University Medical Center, Durham, North Carolina 27710, USA.

  ₄₂Gonzalez, Frank J, ₃Wei, Junping, ₁₀Kuo, Paul C, ₁₅Inoue, Yusuke, ₃Guo, Hongtao.

• Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. (2003) >>

  Dana Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

  ₄₂Gonzalez, Frank J, ₁₃Spiegelman, Bruce M, ₆Rhee, James, ₁Fan, Melina, ₇Puigserver, Pere, ₁₅Inoue, Yusuke, ₃Yoon, J Cliff.

• Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₄Idle, Jeffrey R, ₄₂Gonzalez, Frank J, ₄Küpfer, Adrian, ₅Krausz, Kristopher W, ₅Yu, Ai-ming.

• Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity. (2003) >>

  CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

  ₂Wong, Victoria A, ₄₂Gonzalez, Frank J, ₃Faiola, Brenda, ₄Butterworth, Byron E, ₃Recio, Leslie, ₃Pluta, Linda J, ₂Marchan, Rosemarie, ₁Borghoff, Susan J, ₃Abernethy, Diane J, ₃Bauer, Alison K, ₇Everitt, Jeffrey I.

• Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₄Idle, Jeffrey R, ₄₂Gonzalez, Frank J, ₁Byrd, Linda G, ₄Küpfer, Adrian, ₅Krausz, Kristopher W, ₅Yu, Ai-ming.

• Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1. (2003) >>

  CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

  ₄₂Gonzalez, Frank J, ₁Everitt, Jeffrey, ₁Parkinson, Horace, ₁Borghoff, Susan, ₃Abernethy, Diane J, ₃Bauer, Alison K, ₁Roberts, Kay, ₄Butterworth, Byron E, ₃Faiola, Brenda, ₂Marchan, Rosemarie, ₃Pluta, Linda J, ₃Recio, Leslie, ₄Jaiswal, Anil K, ₁Wong, Vicki A.

• Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. (2003) >>

  Jackson Laboratory, Bar Harbor, ME 04609, USA.

  ₄₂Gonzalez, Frank J, ₄John, Simon W M, ₁Martin, Janice E, ₃Libby, Richard T, ₂Savinova, Olga V, ₁Zabaleta, Adriana, ₆Smith, Richard S.

• Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2. (2003) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

  ₃Kawabe, Mayumi, ₄₂Gonzalez, Frank J, ₃Fernandez-Salguero, Pedro, ₆Kimura, Shioko, ₁Morishima, Hideki, ₁₀Ward, Jerrold M, ₁Hammons, George J, ₂Yu, Aiming, ₁₁Kadlubar, Fred F.

• Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Frederick, Maryland 20892, USA.

  ₁Yim, Sun-Hee, ₄₂Gonzalez, Frank J, ₈Haluzik, Martin, ₅Reitman, Marc L, ₇Gavrilova, Oksana, ₁₀Ward, Jerrold M, ₄Lambert, Gilles, ₃Matsusue, Kimihiko, ₁Brewer, Bryan.

• The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine. (2003) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₄Idle, Jeffrey R, ₄₂Gonzalez, Frank J, ₂Granvil, Camille P, ₂Corchero, Javier, ₄Küpfer, Adrian, ₅Krausz, Kristopher W, ₁Haining, Robert L, ₅Yu, Ai-ming.

• Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle. (2003) >>

  Department of Pathology, Pharmacology and Toxicology, University of Graz, Graz, Austria.

  ₃Brunner, Friedrich, ₄₂Gonzalez, Frank J, ₁Steyrer, Ernst, ₃Hoefler, Gerald, ₈Zechner, Rudolf, ₂Staber, Philipp B, ₁Nöhammer, Christa, ₃Wölkart, Gerald.

• The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. (2003) >>

  Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

  ₁Lan, Lu-Bin, ₄₂Gonzalez, Frank J, ₁Lee, Wooin, ₂Lamba, Vishal, ₈Schuetz, Erin G, ₄Duncan, Stephen A, ₁₃Kim, Richard B, ₂Parviz, Fereshteh, ₁Cline, Cynthia Brimer, ₂Leake, Brenda F, ₁₅Inoue, Yusuke, ₄Tirona, Rommel G.

• CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity. (2003) >>

  Division of Environmental Dermatology and Allergology, GSF/TUM, Centre for Allergy and Environment, Technische Universität München, Biedersteinerstrasse 29, 80802 München, Germany.

  ₄₂Gonzalez, Frank J, ₁Soballa, Volker J, ₂Greim, Helmut, ₃Wolff, Thomas, ₉Quintanilla-Martinez, Leticia, ₁Hintermair, Josef, ₁Buters, Jeroen, ₄Schöber, Wolfgang.

• Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors. (2003) >>

  Laboratory of Metabolism, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.

  ₄₂Gonzalez, Frank J, ₅Akiyama, Taro E.

• Coactivator PRIP, the peroxisome proliferator-activated receptor-interacting protein, is a modulator of placental, cardiac, hepatic, and embryonic development. (2003) >>

  Department of Pathology, Northwestern University, the Feinberg School of Medicine, Chicago, Illinois 60611-3008, USA.

  ₄₂Gonzalez, Frank J, ₈Rao, M Sambasiva, ₄Qi, Chao, ₁₄Crawford, Susan E, ₃Stellmach, Veronica, ₃Zhu, Yi-Jun, ₈Reddy, Janardan K, ₁Dwivedi, Rama S.

• Study of P450 function using gene knockout and transgenic mice. (2003) >>

  Building 37, Room 3E-24, Laboratory of Metabolism, National Cancer Institute, Bethesda, MD 20892, USA.

  ₄₂Gonzalez, Frank J, ₆Kimura, Shioko.

• Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo. (2003) >>

  Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

  ₄₂Gonzalez, Frank J, ₂Jiang, Weiwu, ₂Kondraganti, Sudha R, ₃Fernandez-Salguero, Pedro, ₆Ramos, Kenneth S, ₂Moorthy, Bhagavatula.

• Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. (2003) >>

  Department of Pathology, Northwestern University, the Feinberg School of Medicine, Chicago, Illinois 60611-3008, USA.

  ₁Yeldandi, Vaishalee, ₄₂Gonzalez, Frank J, ₈Rao, M Sambasiva, ₂Cao, Wen-Qing, ₈Reddy, Janardan K, ₂Yeldandi, Anjana V, ₃Matsusue, Kimihiko, ₄Kashireddy, Papreddy, ₅Yu, Songtao.

• The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. (2003) >>

  Molecular Disease Branch, NHLBI, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

  ₄₂Gonzalez, Frank J, ₄Sinal, Christopher J, ₂Amar, Marcelo J A, ₁₀Brewer, H Bryan, ₁Guo, Grace, ₄Lambert, Gilles.