₆₀Shizuo Akira

Shizuo Akira Articles (60) [selected PubMed articles for the year 2003 with the links to a full text at PubMed]

• Too much data, only first 100 publications and/or coauthors will be displayed. Unabridged data can only be viewed as XML or CSV documents.

• Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6. (2003) >>

  Program in Virology, Department of Microbiology and Molecular Genetics, Harvard Medical School, Channing Laboratory/Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115.

  ₂Cahir-McFarland, Ellen, ₉Li, Xiaoxia, ₈Nakano, Hiroyasu, ₁₂Inoue, Jun-Ichiro, ₈Suzuki, Shinobu, ₁Luftig, Micah, ₇Yeh, Wen-Chen, ₁Yasui, Teruhito, ₂Tsichritzis, Theodore, ₆₀Akira, Shizuo, ₈Suzuki, Nobutaka, ₂Mosialos, George, ₃Kieff, Elliott, ₁Prinarakis, Efthimios, ₅Mak, Tak Wah.

• Regulation of dendritic cell function through toll-like receptors. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita Osaka 565-0871, Japan.

  ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo.

• IL-1R-associated kinase 4 is required for lipopolysaccharide-induced activation of APC. (2003) >>

  Advanced Medical Discovery Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

  ₁Mirtosis, Christine, ₂Hwang, Irene, ₂₀Penninger, Josef M, ₈Suzuki, Shinobu, ₁₁Bouchard, Denis, ₇Yeh, Wen-Chen, ₆Wada, Teiji, ₄Hara, Hiromitsu, ₄Chen, Nien-Jung, ₆₀Akira, Shizuo, ₂₆Saito, Takashi, ₈Suzuki, Nobutaka, ₂Der, Sandy, ₈Eriksson, Urs, ₃₄Takeda, Kiyoshi, ₉Fujita, Takashi.

• Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction. (2003) >>

  First Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan.

  ₃Nozaki, Naoki, ₁₄Takahashi, Hiroki, ₆₀Akira, Shizuo, ₁₁Takeishi, Yasuchika, ₄Yamakawa, Mitsunori, ₁Shishido, Tetsuro, ₂Arimoto, Takanori, ₃Nitobe, Joji, ₁₈Kubota, Isao, ₁₇Yamaguchi, Seiji, ₁Maeda, Kunihiko, ₁₂Takeuchi, Osamu, ₂Shibata, Yoko, ₄Miyamoto, Takuya.

• Sequential MyD88-independent and -dependent activation of innate immune responses to intracellular bacterial infection. (2003) >>

  Infectious Disease Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Immunology Program, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10021, USA.

  ₁Rollins, Barrett, ₃Kuziel, William, ₅Flavell, Richard, ₆₀Akira, Shizuo, ₁₀Pamer, Eric G, ₃Serbina, Natalya V.

• Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils. (2003) >>

  Department of Pathology and Experimental Medicine, Graduate School of Medical Sciences, School of Medicine, Kumamoto University, Kumamoto, Japan.

  ₃Matsukawa, Akihiro, ₁Kudo, Shinji, ₁Kagayama, Motoko, ₆₀Akira, Shizuo, ₁Maeda, Takako, ₃₄Takeda, Kiyoshi.

• IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita Osaka 565-0871, Japan.

  ₂Kuwata, Hirotaka, ₄Watanabe, Yasuyuki, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₃Miyoshi, Hiroyuki, ₁₄Yamamoto, Masahiro.

• Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88. (2003) >>

  Rheumatology Research Laboratory and Advanced Therapeutics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

  ₁Koenders, Marije I, ₁Heuvelmans-Jacobs, Marleen, ₆van de Loo, Fons A J, ₂Smeets, Ruben L, ₂Helsen, Monique M A, ₆Joosten, Leo A B, ₆Lubberts, Erik, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₁₄van den Berg, Wim B.

• Antigenic epitopes fused to cationic peptide bound to oligonucleotides facilitate Toll-like receptor 9-dependent, but CD4+ T cell help-independent, priming of CD8+ T cells. (2003) >>

  Department of Medical Microbiology and Immunology, University of Ulm, Ulm, Germany.

  ₈Reimann, Jörg, ₁Riedl, Petra, ₆Zurbriggen, Rinaldo, ₈Schirmbeck, Reinhold, ₆₀Akira, Shizuo.

• TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita Osaka 565-0871, Japan.

  ₆Hemmi, Hiroaki, ₂Hoshino, Katsuaki, ₁₂Takeuchi, Osamu, ₃Uematsu, Satoshi, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₄Sato, Shintaro, ₁₄Yamamoto, Masahiro.

• The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. (2003) >>

  Institute for Medical Microbiology, Hygiene and Immunology, Munich, Germany.

  ₄Hochrein, Hubertus, ₁₆Wagner, Hermann, ₅Bauer, Stefan, ₁Ampenberger, Franziska, ₁Dietrich, Harald, ₆Hemmi, Hiroaki, ₁Lipford, Grayson, ₁Heil, Florian, ₁Gellert, Tanja, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₂Ahmad-Nejad, Parviz.

• X-ray crystal structure of IRF-3 and its functional implications. (2003) >>

  Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo 060-0812, Japan.

  ₁Mori, Mitsuaki, ₂Terasawa, Hiroaki, ₃Horiuchi, Masataka, ₁Suhara, Wakako, ₁Fukuhara, Yukiko, ₉Inagaki, Fuyuhiko, ₁Takahasi, Kiyohiro, ₆Suzuki, Nobuo N, ₆₀Akira, Shizuo, ₁Okabe, Yasutaka, ₉Fujita, Takashi.

• Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis. (2003) >>

  Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room L0185, 1105 AZ Amsterdam, The Netherlands.

  ₃de Vos, Alex F, ₁van der Sluis, Koen, ₁Sewnath, Miguel E, ₂₇van der Poll, Tom, ₁₉Florquin, Sandrine, ₈Gouma, Dirk J, ₃Weijer, Sebastiaan, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Toll-like receptor signaling. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University and ERATO of Japan Science and Technology Corporation, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

  ₆₀Akira, Shizuo.

• Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.

  ₂Kawai, Taro, ₄Watanabe, Yasuyuki, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₂Sugiyama, Masanaka, ₄Sato, Shintaro, ₁₄Yamamoto, Masahiro.

• Immunogenicity of Peptide-25 of Ag85B in Th1 development: role of IFN-gamma. (2003) >>

  Division of Immunology, Department of Microbiology and Immunology, Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

  ₁Kano, Hideyuki, ₉Takatsu, Kiyoshi, ₂₁Iwakura, Yoichiro, ₂Kariyone, Ai, ₄Tamura, Toshiki, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis. (2003) >>

  Graduate Program in Immunology, Graduate School of Medical Sciences, Weill Medical College of Cornell University, Box 62, 1300 York Avenue, New York, NY 10021, USA.

  ₂Schoolnik, Gary, ₆Schnappinger, Dirk, ₁Drenkow, Jorg, ₃Fuortes, Michele, ₃Ding, Aihao, ₁Block, Ellen, ₆₀Akira, Shizuo, ₅Nathan, Carl, ₃₄Takeda, Kiyoshi, ₆Ehrt, Sabine, ₂Gingeras, Thomas R, ₁Shi, Shuangping.

• Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. (2003) >>

  Department of Innovative Surgery, National Research Institute for Child Health and Development, Tokyo, Japan.

  ₆Ogawa, Wataru, ₁Zhang, Hui Qi, ₄Okuyama, Torayuki, ₄Ozaki, Michitaka, ₁Haga, Sanae, ₄Irani, Kaikobad, ₆Enosawa, Shin, ₁Terui, Keita, ₆₀Akira, Shizuo, ₃Ogino, Tetsuya, ₃₄Takeda, Kiyoshi, ₄₁Inoue, Hiroshi.

• Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. (2003) >>

  Fred Hutchinson Cancer Research Center and University of Washington, Seattle, 98109, USA.

  ₂Balajee, S Arunmozhi, ₇Liles, W Conrad, ₇Aderem, Alan, ₄Hawn, Thomas R, ₂Pham, Uyenvy, ₆₀Akira, Shizuo, ₃Ozinsky, Adrian, ₆Marr, Kieren A.

• Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. (2003) >>

  Department of Immunology, Faculty of Medicine and Graduate School of Medicine, University of Tokyo, Japan.

  ₁Watanabe, Ai, ₂Sakaguchi, Shinya, ₁₁Matsumoto, Misako, ₁₂Seya, Tsukasa, ₄Honda, Kenya, ₆Taniguchi, Tadatsugu, ₅Takaoka, Akinori, ₂Nakajima, Chigusa, ₄Yanai, Hideyuki, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₅Ohteki, Toshiaki.

• A critical role for Stat3 signaling in immune tolerance. (2003) >>

  Department of Interdisciplinary Oncology, University of South Florida, Tampa, FL 33612, USA.

  ₁Yu, Hua, ₁₇Wang, Hong-Wei, ₁Ghansah, Tomar, ₆₀Akira, Shizuo, ₂Sotomayor, Eduardo M, ₂Cuenca, Alex, ₁Kerr, William G, ₂Brayer, Jason, ₁₁Jove, Richard, ₈Schoenberger, Stephen P, ₃₄Takeda, Kiyoshi, ₇Huang, Mei, ₄Cheng, Fengdong.

• Integral role of Noxa in p53-mediated apoptotic response. (2003) >>

  Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.

  ₂Morishita, Yasuyuki, ₃Shibue, Tsukasa, ₁Oda, Eri, ₅₈Tanaka, Hiroshi, ₂₀Tanaka, Nobuyuki, ₁Murasawa, Hideki, ₆Taniguchi, Tadatsugu, ₅Takaoka, Akinori, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. (2003) >>

  The Burnham Institute, La Jolla, California 92037, USA.

  ₂Kawai, Taro, ₃₄Reed, John C, ₆₀Akira, Shizuo.

• TLR2 as an essential molecule for protective immunity against Toxoplasma gondii infection. (2003) >>

  Department of Infection and Host Defense, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.

  ₇Mun, Hye-Seong, ₈Yano, Akihiko, ₉Ishikura, Hiroshi, ₇Norose, Kazumi, ₇Aosai, Fumie, ₁₁Chen, Mei, ₅Piao, Lian-Xun, ₁₂Takeuchi, Osamu, ₆₀Akira, Shizuo.

• Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita Osaka 565-0871, Japan.

  ₁₀Okabe, Masaru, ₂Sanjo, Hideki, ₆Hemmi, Hiroaki, ₂Hoshino, Katsuaki, ₁₂Takeuchi, Osamu, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₂Sugiyama, Masanaka, ₄Sato, Shintaro, ₁₄Yamamoto, Masahiro.

• Cutting edge: the B cell chemokine CXC chemokine ligand 13/B lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules. (2003) >>

  Laboratory of Molecular and Cellular Recognition, Osaka University Graduate School of Medicine, Suita, Japan.

  ₂₀Tanaka, Toshiyuki, ₄Yamaguchi, Kazuhito, ₈Miyasaka, Masayuki, ₁Kanemitsu, Naotoshi, ₁₂Kaisho, Tsuneyasu, ₂Ebisuno, Yukihiko, ₆₀Akira, Shizuo, ₂Kanda, Hidenobu.

• CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. (2003) >>

  Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, Tokyo.

  ₄Okochi, Hitoshi, ₂₈Tamaki, Kunihiko, ₆Fujimoto, Manabu, ₉Miyake, Kensuke, ₁₀Tedder, Thomas F, ₃Asano, Noriko, ₁₉Sato, Shinichi, ₂Nagai, Yoshinori, ₂Yazawa, Norihito, ₁₂Takeuchi, Osamu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• [Host defence mechanisms against infections: Innate immunity and adaptive immunity] (2003) >>

  ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo.

• Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guérin peptidoglycan. (2003) >>

  Department of Immunology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.

  ₂Uehori, Junji, ₆Akazawa, Takashi, ₂Toyoshima, Kumao, ₁₁Matsumoto, Misako, ₂Tsuji, Shoutaro, ₃Kawata, Tsutomu, ₁₂Seya, Tsukasa, ₁₂Takeuchi, Osamu, ₃Azuma, Ichiro, ₆₀Akira, Shizuo.

• The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. (2003) >>

  Department of Basic Gerontology, National Institute for Longevity Sciences, 36-3, Gengo, Morioka-cho, Obu, Aichi 474-8522, Japan.

  ₃Kojima, Eiji, ₅Isobe, Ken-ichi, ₆Hasegawa, Tadao, ₂Yagi, Ayako, ₉Shimokata, Kaoru, ₂Haneda, Masataka, ₁Yamaki, Ken-ichi, ₂Takeuchi, Akihide, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. (2003) >>

  Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₆Iwasaki, Akiko, ₃Sato, Ayuko, ₆₀Akira, Shizuo, ₆Medzhitov, Ruslan, ₁Lund, Jennifer.

• Candida albicans phospholipomannan is sensed through toll-like receptors. (2003) >>

  Laboratoire de Mycologie Fondamentale et Appliquée, Inserm EMI0360, Université de Lille II, Lille, France.

  ₁Sacchetti, Paola, ₂Lefebvre, Philippe, ₆Poulain, Daniel, ₃Ibata-Ombetta, Stella, ₄Jouault, Thierry, ₁₂Takeuchi, Osamu, ₃Trinel, Pierre-André, ₆₀Akira, Shizuo.

• CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells. (2003) >>

  Research Center Kyoto, Bayer Yakuhin Ltd., 6-5-1-3 Kunimidai, Kizu-cho, Soraku-gun, Kyoto 619-0216, Japan.

  ₁Ohnishi, Noriko, ₁Liu, Ningshu, ₁Ni, Lin, ₉Bacon, Kevin B, ₆₀Akira, Shizuo.

• Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice. (2003) >>

  Department of Medicine at Karolinska Hospital and Center for Molecular Medicine L8:03, Karolinska Institute, SE-17176 Stockholm, Sweden.

  ₇Rudling, Mats, ₁Jawień, Jacek, ₈Hansson, Göran K, ₆₀Akira, Shizuo, ₁₀Ljunggren, Hans-Gustaf, ₃₄Takeda, Kiyoshi, ₄Bayard, Francis, ₁Elhage, Rima.

• Leptin-induced transactivation of NPY gene promoter mediated by JAK1, JAK2 and STAT3 in the neural cell lines. (2003) >>

  Division of Pharmacology, Department of Molecular Genetics, Course for Molecular and Cellular Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata 951 8510, Japan.

  ₃Tsurumaki, Tatsuru, ₁₇Xu, Bo, ₅Higuchi, Hiroshi, ₄Yamaguchi, Tsuyoshi, ₆₀Akira, Shizuo, ₈Muraoka, Osamu.

• IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. (2003) >>

  Institute of Molecular Medicine and Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0641, USA.

  ₁₂Mori, Hiroyuki, ₆Murakami, Masaaki, ₂Ohishi, Masanobu, ₄Aki, Daisuke, ₆₀Akira, Shizuo, ₁Chinen, Takatoshi, ₃Yasukawa, Hideo, ₅Hoshijima, Masahiko, ₇Hanada, Toshikatsu, ₇Hirano, Toshio, ₃₄Takeda, Kiyoshi, ₂₇Yoshimura, Akihiko, ₁₁Chien, Kenneth R.

• Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, and SORST of Japan Science and Technology, Osaka, Japan.

  ₁Hoshino, Katuaki, ₆₀Akira, Shizuo.

• Regulation of dendritic cell function through Toll-like receptors. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.

  ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo.

• Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis. (2003) >>

  Department of Pediatrics, Vrije Universiteit Medical Center, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

  ₆Roord, John J, ₂₇van der Poll, Tom, ₁₉Florquin, Sandrine, ₅Zwijnenburg, Petra J G, ₅van Furth, A Marceline, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. (2003) >>

  Department of Immunology, University of Washington, Seattle, 98103, USA.

  ₁Simmons, Randi M, ₃Underhill, David M, ₂Canavera, Scott J, ₁Gantner, Benjamin N, ₆₀Akira, Shizuo.

• Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. (2003) >>

  Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.

  ₁Ochoa, Maria Teresa, ₁Ng, Yolanda W, ₄Maeda, Yumi, ₆Sieling, Peter A, ₁Liu, Philip T, ₅Godowski, Paul J, ₁₂Brennan, Patrick J, ₂Krutzik, Stephan R, ₁Legaspi, Annaliza, ₃Rea, Thomas H, ₃Uematsu, Satoshi, ₆₀Akira, Shizuo, ₆Cole, Stewart T, ₄Norgard, Michael V, ₁₂Modlin, Robert L, ₄Sarno, Euzenir N.

• Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. (2003) >>

  Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

  ₆Lakkis, Fadi G, ₂Goldstein, Daniel R, ₁Tesar, Bethany M, ₆₀Akira, Shizuo.

• Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

  ₂Kuwata, Hirotaka, ₁₀Kiyono, Hiroshi, ₃Schreiber, Robert D, ₆Kweon, Mi-Na, ₂Kobayashi, Masaya, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines. (2003) >>

  Immunobiology Laboratory, Cancer Research UK, London Research Institute, London, GB.

  ₆Tomizawa, Hideyuki, ₂Diebold, Sandra S, ₃Edwards, Alexander D, ₆Hemmi, Hiroaki, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₈Reis e Sousa, Caetano, ₁Slack, Emma M C.

• Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa. (2003) >>

  Laboratory of Experimental Internal Medicine, Department of Intensive Care Medicine, C3-326, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

  ₁Schultz, Marc J, ₂₇van der Poll, Tom, ₁₉Florquin, Sandrine, ₅Knapp, Sylvia, ₃Pater, Jennie, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells. (2003) >>

  Department of Medicine and The Sam and Rose Stein Institute for Research on Aging, University of California, La Jolla, CA 92093, USA.

  ₆Raz, Eyal, ₃Redecke, Vanessa, ₁DiDonato, Joseph, ₃Dziarski, Roman, ₁Prilliman, Kiley R, ₃Takabayashi, Kenji, ₁Tallant, Thomas, ₆₀Akira, Shizuo, ₆Corr, Maripat, ₈Schoenberger, Stephen P, ₂Datta, Sandip K.

• Toll receptors and pathogen resistance. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, and SORST of Japan Science and Technology Corporation, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

  ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Toll-like receptor-mediated tyrosine phosphorylation of paxillin via MyD88-dependent and -independent pathways. (2003) >>

  Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Minami-ku, Hiroshima 734-8551, Japan.

  ₃Funami, Kenji, ₁₁Matsumoto, Misako, ₁₂Seya, Tsukasa, ₁Masuda, Naoyo, ₃Hazeki, Osamu, ₁Hazeki, Kaoru, ₂Sukenobu, Naoe, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University and Solution-Oriented Research for Science and Technology, Japan Science and Technology Corp., Suita, Osaka, Japan.

  ₆Hemmi, Hiroaki, ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent OK-432. (2003) >>

  Second Department of Oral and Maxillofacial Surgery, Tokushima University School of Dentistry, 3-18-15 Kuramoto-cho, Tokushima 770 8504, Japan.

  ₂Ohe, Go, ₉Miyake, Kensuke, ₃Moriya, Yoichiro, ₆₀Akira, Shizuo, ₁Tano, Tomoyuki, ₂Nishikawa, Hidetomo, ₁Ahmed, Sharif Uddin, ₂Oshikawa, Tetsuya, ₂Saito, Motoo, ₃Matsubara, Shuzo, ₃Okamoto, Masato, ₁₂Takeuchi, Osamu, ₃Akashi, Sachiko, ₂Ryoma, Yoshiki, ₉Sato, Mitsunobu, ₂Furuichi, Sachiko.

• TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.

  ₆Tsujimura, Tohru, ₂Sanjo, Hideki, ₈Ninomiya-Tsuji, Jun, ₁₁Matsumoto, Kunihiro, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Mammalian Toll-like receptors. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

  ₆₀Akira, Shizuo.

• Prion pathogenesis in the absence of Toll-like receptor signalling. (2003) >>

  University Hospital of Zürich, Zürich, Switzerland.

  ₆Prinz, Marco, ₄Heikenwalder, Mathias, ₃Schwarz, Petra, ₁₆Aguzzi, Adriano, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2. (2003) >>

  Lymphocyte development, URA-1961 of the National Center for Scientific Research, Pasteur Institute, Paris, France.

  ₆Chignard, Michel, ₅Pedron, Thierry, ₄Girard, Robert, ₃Uematsu, Satoshi, ₆₀Akira, Shizuo, ₃Balloy, Viviane, ₆Chaby, Richard.

• Synergistic effects of lipopolysaccharide and interferon-gamma in inducing interleukin-8 production in human monocytic THP-1 cells is accompanied by up-regulation of CD14, Toll-like receptor 4, MD-2 and MyD88 expression. (2003) >>

  Department of Microbiology and Immunology, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

  ₄Tamai, Riyoko, ₅Takada, Haruhiko, ₅Sugawara, Shunji, ₁₂Takeuchi, Osamu, ₆₀Akira, Shizuo.

• Toll-like receptors. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita Osaka 565-0871, Japan.

  ₁₂Kaisho, Tsuneyasu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi.

• Toll-like receptors and their signaling mechanisms. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.

  ₆₀Akira, Shizuo, ₄Sato, Shintaro.

• Mycobacterial infection in MyD88-deficient mice. (2003) >>

  Mycobacterial Reference Center, The Research Institute of Tuberculosis, Kiyose, Tokyo, Japan.

  ₃Mizuno, Satoru, ₈Sugawara, Isamu, ₆₀Akira, Shizuo, ₃₄Takeda, Kiyoshi, ₁₁Yamada, Hiroyuki.

• Mycobacterial infection in TLR2 and TLR6 knockout mice. (2003) >>

  Department of Molecular Pathology, The Research Institute of Tuberculosis, Kiyose, Tokyo 204-0022, Japan.

  ₃Mizuno, Satoru, ₂Li, Chuanyou, ₁₂Takeuchi, Osamu, ₈Sugawara, Isamu, ₆₀Akira, Shizuo, ₁₁Yamada, Hiroyuki.

• Recognition of pathogen-associated molecular patterns by TLR family. (2003) >>

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, SORST of Japan Science and Technology Corporation, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

  ₆Hemmi, Hiroaki, ₆₀Akira, Shizuo.