6Miriam H Meisler
Summary for 2004 [at-glance overview of Miriam H Meisler work for the selected year as suggested by data mining algorithms]
This is an Authoratory overview of author Miriam H Meisler. According to available data, in 2004 Miriam H Meisler published at least 6 articles. This work was completed in collaboration with several authors including Adamska, Maja and Buchner, David A. Many other authors have collaborated with Miriam H Meisler as well. At least 8 different grants are awarded to Miriam H Meisler to support this work. All time total of the grant awards on file exceeds $14,630,153.
Miriam H Meisler has rank 55 when compared to all other authors using the keyword Sodium Channels. Analysis of the article abstracts and the titles suggests that Miriam H Meisler professional interests are focused around "sodium channel scn8a", "allele conditional inactivation" and "paralysis juvenile lethality". These might also be referred to as "sodium channel", "omi htra2" or "channel scn8a". Statistical analysis shows that Miriam H Meisler's writing is likely to contains terms "scn8a", "mutations", "dkk1", "channel", "sodium" and "mouse".
The majority of Miriam H Meisler articles are affiliated with Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan MI 48109-0618, USA. Luckily, one email address is on file.
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Year 2004 Charts [Miriam H Meisler frequent coauthors and the most common unique vocabulary terms for the selected year]
Historical Performance Charts [graphical overview of Miriam H Meisler publication and funding history for the range of years]
Emails (1) [email addresses extracted from Miriam H Meisler affiliations]
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Miriam H Meisler Coauthors (16) [all coauthors with the number of joint publications]
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Affiliations (2) [condensed summary of the Miriam H Meisler affiliations, the leading number and the color conveys importance]
- 5Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan MI 48109-0618, USA.
1Center for Apoptosis Research and the Department of Microbiology and Immunology, Kimmel Cancer Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Key Opinion Leader In [Miriam H Meisler is considered a key opinion leader in any keyword where the rank of 5 is achieved, the leading number before the keyword shows the author's rank as compared to all other authors]
- 55Sodium Channels | 211Alleles | 296Nerve Tissue Proteins
Keywords (32) [keywords assigned to Miriam H Meisler articles by PubMed, the leading number and the color conveys importance]
- 5Mice | 5Animals | 3Nerve Tissue Proteins | 3Alleles | 3Molecular Sequence Data | 3Sodium Channels | 2Limb Deformities, Congenital | 2Mice, Mutant Strains | 2Gene Expression Regulation, Developmental | 2Genetic Complementation Test | 2Mice, Transgenic | 2Amino Acid Sequence | 2Proteins | 2Intercellular Signaling Peptides and Proteins | 1Base Sequence | 1Gene Dosage | 1Fetal Death | 1Homeodomain Proteins | 1Hela Cells | 1Sequence Homology, Amino Acid | 1Wnt Proteins | 1Nervous System Diseases | 1Protein Structure, Secondary | 1Gene Targeting | 1Ectoderm | 1Proto-Oncogene Proteins | 1Exons | 1Genes, Recessive | 1Muscle Weakness | 1Mitochondrial Proteins | 1Gene Silencing | 1Ethylnitrosourea
Miriam H Meisler Unique Vocabulary (96) [single words, word pairs and phrases obtained by analysis of abstracts and titles, the leading number and the color conveys importance; Miriam H Meisler might be a good expert witness on these terms]
- 21scn8a | 16mutations | 16dkk1 | 14channel | 13sodium | 11mouse | 11mice | 10null | 10wnt7a | 9allele | 9omi | 7lrp6 | 7expression | 7wnt | 6en1 | 6floxed | 6mutants | 6nav1 | 6alleles | 6signaling | 6doubleridge | 5inactivation | 5double | 5severe | 5rd13 | 5neurological | 5loss | 5mutant | 3disorders | 3several | 3cellular | 3cell
- 12sodium channel | 7omi htra2 | 6channel scn8a | 5floxed allele | 5wnt signaling | 4double mutants | 4null mice | 3expression dkk1 | 3c-terminal tail | 3compensatory interactions | 3protease activity | 3dkk1d den1 | 3allele conditional | 3mutation rd13 | 3allelic mutations | 3en1 wnt7a | 3conditional inactivation | 3limb development | 2dependence compensatory | 2regulates omi | 2presenilin regulates | 2multiple cellular | 2interactions lrp6 | 2extra digits | 2lrp5 lrp6 | 2scn8a del | 2voltage-gated sodium | 2htra2 protease | 2inactivation voltage-gated | 2alleles scn8a | 2dose dependence | 2complete loss
- 6sodium channel scn8a | 3allele conditional inactivation | 2paralysis juvenile lethality | 2voltage-gated sodium channel | 2c-terminal tail presenilin | 2omi htra2 protease | 2presenilin regulates omi | 2scn8a reveal multiple | 2dkk1 doubleridge mouse | 2expression dkk1 doubleridge | 2dose dependence compensatory | 2dependence compensatory interactions | 2allelic mutations sodium | 2mouse dose dependence | 2doubleridge mouse dose | 2regulates omi htra2 | 2hypomorphic expression dkk1 | 2htra2 protease activity | 2tail presenilin regulates | 2reveal multiple cellular | 2cellular physiological functions | 2conditional inactivation voltage-gated | 2floxed allele conditional | 2compensatory interactions lrp6 | 2channel scn8a reveal | 2activity omi htra2 | 2channel scn8a nav1 | 2inactivation voltage-gated sodium | 2mutations sodium channel | 2multiple cellular physiological | 2interact dkk1 limb | 2neurological mutations pore
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Funding (8) [selected NIH grants to Miriam H Meisler and the award amounts for recent years]
- HORMONAL REGULATION OF AMYLASE GENE EXPRESSION (MEISLER, MIRIAM - 1985)
Grant # Award Year Award Amount, USD award information is not available Total up to 2004 $NA - PIROUETE MOUSE DEAFNESS MUTANT (MEISLER, MIRIAM - 1997)
Grant # Award Year Award Amount, USD 1P01DC002982-01A1 1997 $1,020,030 5P01DC002982-02 1998 $1,050,639 5P01DC002982-03 1999 $1,082,158 3P01DC002982-04S1 2000 $20,000 3P01DC002982-04S2 2000 $48,605 3P01DC002982-04S3 2000 $49,987 5P01DC002982-04 2000 $1,114,632 5P01DC002982-05 2001 $1,147,762 Total up to 2004 $5,533,813 - AMYLASE REGULATION IN HUMAN SALIVARY GLANDS (MEISLER, MIRIAM - 1986)
Grant # Award Year Award Amount, USD award information is not available Total up to 2004 $NA - <TITLE UNKNOWN> (MEISLER, MIRIAM H - 1992)
Grant # Award Year Award Amount, USD 5R01DK036089-08 1992 $210,971 5R01DK036089-09 1993 $224,001 Total up to 2004 $434,972 - GENETIC REGULATION OF BETA-GALACTOSIDASE (MEISLER, MIRIAM - 1974)
Grant # Award Year Award Amount, USD 1F32GM020889-01 2001 $20,098 Total up to 2004 $20,098 - GENETIC REGULATION OF MOUSE ENZYMES (MEISLER, MIRIAM - 1977)
Grant # Award Year Award Amount, USD 2R01GM024872-15 1992 $240,694 5R01GM024872-16 1993 $229,079 5R01GM024872-17 1994 $243,726 5R01GM024872-18 1995 $252,698 2R01GM024872-19 1996 $256,761 5R01GM024872-20 1997 $267,925 5R01GM024872-21 1998 $278,352 5R01GM024872-22 1999 $289,194 2R01GM024872-23A1 2000 $322,386 5R01GM024872-24 2001 $321,244 3R01GM024872-25S1 2002 $18,120 5R01GM024872-25 2002 $321,142 5R01GM024872-26 2003 $339,157 2R01GM024872-27 2004 $380,484 Total up to 2004 $3,760,962 - NEUROMUSCULAR DISEASE GENE ENCODING A NEW SODIUM CHANNEL (MEISLER, MIRIAM - 1996)
Grant # Award Year Award Amount, USD 1R01NS034509-01A1 1996 $233,360 5R01NS034509-02 1997 $217,600 5R01NS034509-03 1998 $226,305 5R01NS034509-04 1999 $235,357 5R01NS034509-05 2000 $244,771 2R01NS034509-06 2001 $294,280 3R01NS034509-07S1 2002 $18,120 5R01NS034509-07 2002 $298,213 3R01NS034509-08S1 2003 $20,000 5R01NS034509-08 2003 $316,443 5R01NS034509-09 2004 $316,219 Total up to 2004 $2,420,668 - DNA SEQUENCER AND OLIGO SYNTHESIZER (MEISLER, MIRIAM - 1989)
Grant # Award Year Award Amount, USD award information is not available Total up to 2004 $NA
Miriam H Meisler Articles (6) [selected PubMed articles for the year 2004 with the links to a full text at PubMed]
The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity. (2004) >>
Center for Apoptosis Research and the Department of Microbiology and Immunology, Kimmel Cancer Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
4Alnemri, Emad S, 2Zhang, ZhiJia, 4Zervos, Antonis S, 6Meisler, Miriam H, , , 1Datta, Pinaki, , 3Singh, Rajesh, 9Gupta, Sanjeev, 3Srinivasula, Srinivasa M, 2Fernandes-Alnemri, Teresa.Allelic mutations of the sodium channel SCN8A reveal multiple cellular and physiological functions. (2004) >>
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-0618, USA.
3Plummer, Nicholas W, 6Meisler, Miriam H, 2Buchner, David A, , 1Sprunger, Leslie K.Floxed allele for conditional inactivation of the voltage-gated sodium channel Scn8a (NaV1.6). (2004) >>
Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan 48109-0618, USA.
6Meisler, Miriam H, 1Levin, Stephen I.En1 and Wnt7a interact with Dkk1 during limb development in the mouse. (2004) >>
Department of Human Genetics, University of Michigan, Ann Arbor 48109-0618, USA.
6Meisler, Miriam H, , 2Adamska, Maja, 2MacDonald, Bryan T, .Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. (2004) >>
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-0618, USA.
6Meisler, Miriam H, 2Adamska, Maja, 2MacDonald, Bryan T.Three ENU-induced neurological mutations in the pore loop of sodium channel Scn8a (Na(v)1.6) and a genetically linked retinal mutation, rd13. (2004) >>
Department of Human Genetics, University of Michigan, Ann Arbor 48109-0618, USA.
10Frankel, Wayne N, 6Meisler, Miriam H, 2Seburn, Kevin L, 2Buchner, David A.
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