3Irving H Goldberg
Summary for 2004 [at-glance overview of Irving H Goldberg work for the selected year as suggested by data mining algorithms]
This is an Authoratory overview of author Irving H Goldberg. According to available data, in 2004 Irving H Goldberg published at least 3 articles. This work was completed in collaboration with several authors including Jones, Graham B and Hwang, Geum-Sook. At least 3 different grants are awarded to Irving H Goldberg to support this work. All time total of the grant awards on file exceeds $11,943,199.
Irving H Goldberg has rank 600 when compared to all other authors using the keyword DNA. Analysis of the article abstracts and the titles suggests that Irving H Goldberg professional interests are focused around "dna bulge binder", "chiral spirocyclic helical" and "ddi-bulged dna complex". These might also be referred to as "bulged dna", "dna bulge" or "bulge binder". Statistical analysis shows that Irving H Goldberg's writing is likely to contains terms "dna", "bulge", "spirocyclic", "binding", "bulged" and "nmr".
The majority of Irving H Goldberg articles are affiliated with Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. Sadly, no email addresses were found for any of the affiliations.
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Year 2004 Charts [Irving H Goldberg frequent coauthors and the most common unique vocabulary terms for the selected year]
Historical Performance Charts [graphical overview of Irving H Goldberg publication and funding history for the range of years]
Irving H Goldberg Coauthors (4) [all coauthors with the number of joint publications]
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Affiliations (2) [condensed summary of the Irving H Goldberg affiliations, the leading number and the color conveys importance]
- 2Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
1Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Key Opinion Leader In [Irving H Goldberg is considered a key opinion leader in any keyword where the rank of 5 is achieved, the leading number before the keyword shows the author's rank as compared to all other authors]
- 600DNA
Keywords (19) [keywords assigned to Irving H Goldberg articles by PubMed, the leading number and the color conveys importance]
- 3DNA | 2Oligonucleotides | 2Binding Sites | 2Nucleic Acid Conformation | 2Stereoisomerism | 1Base Sequence | 1Nuclear Magnetic Resonance, Biomolecular | 1Cyclization | 1Crystallography, X-Ray | 1Zinostatin | 1Spiro Compounds | 1Alkylating Agents | 1Molecular Conformation | 1Nucleic Acid Heteroduplexes | 1Magnetic Resonance Spectroscopy | 1Circular Dichroism | 1Models, Molecular | 1Intercalating Agents | 1Enediynes
Irving H Goldberg Unique Vocabulary (96) [single words, word pairs and phrases obtained by analysis of abstracts and titles, the leading number and the color conveys importance; Irving H Goldberg might be a good expert witness on these terms]
- 18dna | 13bulge | 11spirocyclic | 10binding | 7bulged | 6nmr | 5ent-ddi | 5helical | 5complex | 4natural | 4molecule | 3ddi | 3positioned | 3direction | 3agents | 3chiral | 3comparison | 3study | 3complexes | 3moiety | 3site | 3designed | 3binder | 3synthesis | 3alkylation | 3bases | 2aminoglycoside | 2stereochemical | 2formed | 2enantiomer-bulged | 2cd | 2ddi-bulged
- 5bulged dna | 3dna bulge | 3bulge binder | 3dna complex | 3chiral spirocyclic | 3spirocyclic helical | 2molecule binding | 2structures spirocyclic | 2dna microenvironments | 2stereochemical control | 2dna comparison | 2alkylation agents | 2binding bulged | 2helical duplex | 2nmr binding | 2analogue natural | 2synthesis nmr | 2bulge site | 2preparation alkylation | 2spirocyclic enantiomer-bulged | 2two-base bulge | 2natural dna | 2control small | 2agents bulged | 2spirocyclic enantiomers | 2small molecule | 2study chiral | 2moiety ent-ddi | 2binding study | 2ent-ddi-bulged dna | 2dna complexes | 2ddi-bulged dna
- 3dna bulge binder | 3chiral spirocyclic helical | 2ddi-bulged dna complex | 2analogue natural dna | 2control small molecule | 2bulged dna comparison | 2preparation alkylation agents | 2molecule binding bulged | 2nmr binding study | 2agents bulged dna | 2alkylation agents bulged | 2binding study chiral | 2stereochemical control small | 2natural dna bulge | 2structures spirocyclic enantiomer-bulged | 2helical analogue natural | 2small molecule binding | 2study chiral spirocyclic | 2bulged dna microenvironments | 2synthesis nmr binding | 2enantiomer-bulged dna complexes | 2spirocyclic helical analogue | 2binding bulged dna | 2comparison structures spirocyclic | 2spirocyclic enantiomer-bulged dna | 2dna comparison structures | 1binding characteristics synthetic | 1extrahelical ddi-bulged dna | 1specific bulged sequences | 1dna elucidation detailed | 1microenvironments designed molecule | 1geometry natural product
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Funding (3) [selected NIH grants to Irving H Goldberg and the award amounts for recent years]
- MOLECULAR PHARMACOLOGY OF ANTICANCER DRUGS (GOLDBERG, IRVING - 1988)
Grant # Award Year Award Amount, USD 5R35CA044257-05 1992 $844,259 5R35CA044257-06 1993 $854,817 5R35CA044257-07 1994 $844,657 3R35CA044257-07S1 1995 $90,000 Total up to 2004 $2,633,733 - PREDOCTORAL TRAINING IN PHARMACOLOGICAL SCIENCES (GOLDBERG, IRVING - 1975)
Grant # Award Year Award Amount, USD 5T32GM007306-18 1992 $269,922 5T32GM007306-19 1993 $286,769 5T32GM007306-20 1994 $302,420 5T32GM007306-21 1995 $281,457 2T32GM007306-22A1 1997 $224,453 5T32GM007306-23 1998 $226,631 5T32GM007306-24 1999 $252,032 5T32GM007306-25 2000 $266,432 2T32GM007306-26 2001 $304,072 5T32GM007306-27 2002 $320,108 5T32GM007306-28 2003 $335,764 5T32GM007306-29 2004 $342,710 Total up to 2004 $3,412,770 - MOLECULAR MECHANISMS OF NUCLEIC ACID DAMAGE BY ENEDIYNES (GOLDBERG, IRVING - 1996)
Grant # Award Year Award Amount, USD 1R01GM053793-01 1996 $311,466 5R01GM053793-02 1997 $321,604 5R01GM053793-03 1998 $332,146 5R01GM053793-04 1999 $343,111 2R01GM053793-05 2000 $386,858 5R01GM053793-06 2001 $382,461 5R01GM053793-07 2002 $391,372 5R01GM053793-08 2003 $400,552 2R01GM053793-09A1 2004 $358,757 3R01GM053793-08S1 2004 $131,188 Total up to 2004 $3,359,515
Irving H Goldberg Articles (3) [selected PubMed articles for the year 2004 with the links to a full text at PubMed]
Synthesis and NMR binding study of a chiral spirocyclic helical analogue of a natural DNA bulge binder. (2004) >>
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
3Goldberg, Irving H, 2Hwang, Geum-Sook, 1Gaikwad, Nilesh W.Preparation of alkylation agents for bulged DNA microenvironments. (2004) >>
Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
1Xi, Zhen, 3Goldberg, Irving H, 3Jones, Graham B, .Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes. (2004) >>
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
3Goldberg, Irving H, 3Jones, Graham B, 2Hwang, Geum-Sook.
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