₄₁Richard A Flavell

Richard A Flavell Articles (41) [selected PubMed articles for the year 2007 with the links to a full text at PubMed]

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• Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. (2007) >>

  Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₅Sutterwala, Fayyaz S, ₂₂₉Li, Li, ₄₁Flavell, Richard A, ₁Mijares, Lilia A, ₂Kazmierczak, Barbara I, ₄Ogura, Yasunori.

• A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. (2007) >>

  [1] Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Cambridge, Massachusetts 02139, USA. [2] These authors contributed equally to this work.

  ₁₁Bettelli, Estelle, ₁₄Oukka, Mohamed, ₄₁Flavell, Richard A, ₁₂Weiner, Howard L, ₃Kamanaka, Masahito, ₃Awasthi, Amit, ₁₅Kuchroo, Vijay K, ₃Carrier, Yijun, ₁Peron, Jean P S.

• 'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation. (2007) >>

  Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

  ₄₁Flavell, Richard A, ₅Wan, Yisong Y.

• MKK3-p38 signaling promotes apoptosis and the early inflammatory response in the obstructed mouse kidney. (2007) >>

  Department of Nephrology, Monash Medical Centre, 246 Clayton Rd., Clayton, Victoria 3168, Australia.

  ₄₁Flavell, Richard A, ₃Nikolic-Paterson, David J, ₂Ma, Frank Y, ₄Tesch, Greg H, ₁₆Davis, Roger J.

• COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. (2007) >>

  Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06511, USA.

  ₂Menon, Suchithra, ₁₁Deng, Xing Wang, ₆Wei, Ning, ₄₁Flavell, Richard A, ₃Chi, Hongbo, ₂Zhang, Huiyong.

• Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. (2007) >>

  Laboratory of Immunogenetics, NIAID/NIH, Rockville, MD 20852, USA.

  ₄Bolland, Silvia, ₈Town, Terrence, ₁₀Feigenbaum, Lionel, ₄₁Flavell, Richard A, ₃Deane, Jonathan A, ₁₀Ward, Jerrold M, ₁Pisitkun, Prapaporn, ₁Barrett, Rebecca S.

• CD86 has sustained costimulatory effects on CD8 T cells. (2007) >>

  Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.

  ₁Thomas, Ian J, ₁Guerder, Sylvie, ₄Wong, F Susan, ₄₁Flavell, Richard A, ₁Petrich de Marquesini, Liliana G, ₁Wraith, David C, ₄Ravanan, Rommel, ₃Smith, Richard M, ₇Wen, Li.

• IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice. (2007) >>

  Immunopathogenesis Section, Laboratory of Parasitic Diseases, and Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.

  ₄Keane-Myers, Andrea, ₁Elnekave, Eldad, ₇Thompson, Robert W, ₃Hodges, Marcus G, ₃Mentink-Kane, Margaret M, ₄₁Flavell, Richard A, ₁Cheever, Allen W, ₆Wynn, Thomas A, ₃Kamanaka, Masahito, ₂Pesce, John T, ₄Wilson, Mark S, ₂Ramalingam, Thirumalai R.

• Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells. (2007) >>

  Department of Dermatology, 2Department of Laboratory Medicine, 3Section of Immunobiology, and 4Section of Medical Oncology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₃Kaplan, Daniel H, ₉Shlomchik, Mark J, ₁Jenison, Matthew C, ₄₁Flavell, Richard A, ₃Shlomchik, Warren D, ₄Li, Ming O.

• Suppression of p53-dependent senescence by the JNK signal transduction pathway. (2007) >>

  Program in Molecular Medicine, Department of Cancer Cell Biology, and Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.

  ₃₆Zhang, Chao, ₂₀Shokat, Kevan M, ₁Das, Madhumita, ₄₁Flavell, Richard A, ₃₀Jiang, Feng, ₂Sluss, Hayla K, ₁₆Davis, Roger J.

• Demethylation of a specific hypersensitive site in the Th2 locus control region. (2007) >>

  Department of Immunobiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₂Kim, Sean T, ₄₁Flavell, Richard A, ₁Fields, Patrick E.

• Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery. (2007) >>

  Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.

  ₁Chai, Gui-Xuan, ₁Yang, Derek D, ₂Jacoby, Joerg J, ₁₅Gao, Bin, ₂Fu, Xin-Yuan, ₄₁Flavell, Richard A, ₁₂Zhang, Wenjun, ₄Iwamoto, Yoshiki, ₁₉₄Wang, Jun, ₁Zhang, Samual Shao-Min, ₇Kano, Arihiro, ₁Moh, Akira.

• Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. (2007) >>

  Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₅Valenzuela, David M, ₁Karow, Margaret, ₄₁Flavell, Richard A, ₃Zenewicz, Lauren A, ₃Murphy, Andrew J, ₁₅Yancopoulos, George D.

• ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection. (2007) >>

  Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₂Pedra, Joao H F, ₅Sutterwala, Fayyaz S, ₄Montgomery, Ruth R, ₂₁Qian, Feng, ₄₁Flavell, Richard A, ₄Sukumaran, Bindu, ₁₇Fikrig, Erol, ₄Ogura, Yasunori.

• Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. (2007) >>

  Lineberger Comprehensive Cancer Center, Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

  ₃Bergstralh, Daniel T, ₃Deshmukh, Mohanish, ₂Morrison, Amy C, ₄₁Flavell, Richard A, ₂Willingham, Stephen B, ₈Ting, Jenny P-Y, ₄Taxman, Debra J, ₁O'Connor, William, ₈Hoffman, Hal M, ₁BarNoy, Shoshana, ₂Venkatesan, Malabi M, ₃Duncan, Joseph A.

• Requirement of JIP scaffold proteins for NMDA-mediated signal transduction. (2007) >>

  Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

  ₁₁Rakic, Pasko, ₄₁Flavell, Richard A, ₂Martin, Gilles, ₁Ehrhardt, Anka G, ₃Kennedy, Norman J, ₁₆Davis, Roger J, ₁Cavanagh-Kyros, Julie, ₄Kuan, Chia-Yi, ₄Treistman, Steven N.

• Transforming growth factor-beta and the immune response: implications for anticancer therapy. (2007) >>

  Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.

  ₄₁Flavell, Richard A, ₅Wan, Yisong Y, ₂Wrzesinski, Stephen H.

• Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections. (2007) >>

  Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.

  ₃Ha, Un-Hwan, ₇Koga, Tomoaki, ₄₁Flavell, Richard A, ₄Bourne, Patricia, ₁₁Yan, Chen, ₄Woo, Chang-Hoon, ₄Zhang, Wenhong, ₁Stirling, Brigid, ₅Yin, Zhinan, ₆Jono, Hirofumi, ₆Xu, Haidong, ₉Li, Jian-Dong, ₂Huang, Yuxian, ₃Ishinaga, Hajime, ₂Zhu, Hongguang, ₇Feng, Xin-Hua, ₄Lim, Jae Hyang, ₉Briles, David E, ₂Andalibi, Ali, ₉Xu, Haodong, ₁Derry, Jonathan, ₁₆Davis, Roger J, ₂Weng, Xinhua.

• The inflammasome in pathogen recognition and inflammation. (2007) >>

  Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

  ₅Sutterwala, Fayyaz S, ₄₁Flavell, Richard A, ₄Ogura, Yasunori.

• IL-12/23p40-dependent clearance of Anaplasma phagocytophilum in the murine model of human anaplasmosis. (2007) >>

  Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₂Pedra, Joao H F, ₅Sutterwala, Fayyaz S, ₄₁Flavell, Richard A, ₂Berliner, Nancy, ₄Sukumaran, Bindu, ₁₇Fikrig, Erol, ₅Yin, Zhinan, ₃Bockenstedt, Linda K, ₄Tao, Jian.

• Regulatory T cells, transforming growth factor-beta, and immune suppression. (2007) >>

  Section of Immunobiology, Yale University School of Medicine, 300 Cedar Street, TAC S-569, New Haven, CT 06520, USA.

  ₄₁Flavell, Richard A, ₅Wan, Yisong Y.

• Immunology: sensing the enemy within. (2007) >>

  ₄₁Flavell, Richard A, ₃Chi, Hongbo.

• c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. (2007) >>

  Department of Pathology, University of Illinois at Chicago, Room 113 CSN, Chicago, IL 60612, USA.

  ₄₁Flavell, Richard A, ₂Song, Zibo, ₄Augenlicht, Leonard H, ₂Tong, Chang, ₂Mariadason, John, ₁₃Huang, Chuanshu, ₄Yang, WanCai, ₂Dockendorff, Ashley, ₅Yin, Zhinan, ₁₆Davis, Roger J.

• MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3. (2007) >>

  Department of Immunology, The Scripps Research Institute, La Jolla, California, USA.

  ₅Sutterwala, Fayyaz S, ₄Ulevitch, Richard J, ₁Kravchenko, Vladimir V, ₄₁Flavell, Richard A, ₁Grant, Ethan P, ₄Ogura, Yasunori, ₇Coyle, Anthony J, ₂Pan, Qilin, ₁Fearns, Colleen, ₁Kobayashi, Koichi S, ₂Bertin, John, ₃Mathison, John, ₈Hoffman, Hal M, ₄da Silva Correia, Jean.

• Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. (2007) >>

  Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₆Jankovic, Dragana, ₁₁Busslinger, Meinrad, ₄₁Flavell, Richard A, ₈Sher, Alan, ₉Radtke, Freddy, ₁Amsen, Derk, ₁₁Gridley, Thomas, ₁Antov, Andrey, ₁McCright, Brent, ₂Souabni, Abdallah.

• Epigenetic regulation of Ifng expression. (2007) >>

  ₄₁Flavell, Richard A, ₁Spilianakis, Charalampos G.

• Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure. (2007) >>

  Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4TJ, UK.

  ₂Henderson, Neil C, ₁Simpson, Kenneth J, ₂Mackinnon, Alison C, ₄₁Flavell, Richard A, ₂Sethi, Tariq, ₁₆Davis, Roger J, ₁Pollock, Katharine J, ₂Frew, John.

• Post-infarction remodeling is independent of mitogen-activated protein kinase kinase 3 (MKK3). (2007) >>

  The Cardiovascular Division, Kings College London, The Rayne Institute, St Thomas' Hospital, London, UK.

  ₂Heads, Richard J, ₄₁Flavell, Richard A, ₁Faircloth, Matthew E, ₈Marber, Michael S, ₃Clark, James E, ₁₆Davis, Roger J.

• Deletion of the c-Jun N-terminal kinase 3 gene protects neonatal mice against cerebral hypoxic-ischaemic injury. (2007) >>

  Division of Clinical Sciences, Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK.

  ₁₃Edwards, A David, ₁₁Mallard, Carina, ₄₁Flavell, Richard A, ₁Pirianov, Grisha, ₁₆Hagberg, Henrik, ₂Brywe, Katarina G, ₂Mehmet, Huseyin.

• T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. (2007) >>

  Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₄₁Flavell, Richard A, ₅Wan, Yisong Y, ₄Li, Ming O.

• Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis. (2007) >>

  University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

  ₄Hakem, Razqallah, ₁Mohapatra, Alexander, ₁Ferrandino, Anthony, ₁Lakhani, Saquib A, ₄₁Flavell, Richard A, ₁Masud, Ali.

• TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules. (2007) >>

  Institute for Antiviral Research, Utah State University, Logan, Utah 84341, USA.

  ₂Mitchell, William M, ₂Jung, Kie-Hoon, ₄₁Flavell, Richard A, ₄Gowen, Brian B, ₁₂Sidwell, Robert W, ₅Alexopoulou, Lena, ₆Wong, Min-Hui, ₂Sanders, Andrew B.

• Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells. (2007) >>

  Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.

  ₉Reiner, Steven L, ₂He, Weifeng, ₁Harvey, Bohdan, ₂Kim, Sean T, ₄₁Flavell, Richard A, ₃Chi, Hongbo, ₃₇Chen, Liang, ₂Gao, Yunfei, ₁Craft, Joe, ₅Yin, Zhinan, ₄Intlekofer, Andrew M, ₄Tao, Jian.

• JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response. (2007) >>

  Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT 06520-8031, USA.

  ₂He, Weifeng, ₄₁Flavell, Richard A, ₃₇Chen, Liang, ₂Gao, Yunfei, ₅Yin, Zhinan, ₁Harvev, Bohdan, ₁₆Davis, Roger J, ₄Li, Ming O, ₄Tao, Jian.

• Antiviral peptides targeting the west nile virus envelope protein. (2007) >>

  Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₈Town, Terrence, ₂Ashish, ₂Pradhan, Deepti, ₇Cox, Jonathan, ₄₁Flavell, Richard A, ₃Koski, Raymond A, ₁₇Fikrig, Erol, ₂Krueger, Joanna K, ₃Ledizet, Michel, ₇Anderson, John F, ₁Bai, Fengwei.

• Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. (2007) >>

  Immunobiology Section and 2Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

  ₆Jankovic, Dragana, ₅Feng, Carl G, ₁Collazo, Carmen M, ₄₁Flavell, Richard A, ₈Sher, Alan, ₆Wynn, Thomas A, ₃Kamanaka, Masahito, ₆Wilson, Mark, ₂Goldszmid, Romina S, ₁Kullberg, Marika C.

• Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. (2007) >>

  Section of Immunobiology, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut 06520, USA.

  ₄₁Flavell, Richard A, ₅Wan, Yisong Y.

• Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. (2007) >>

  Department of Medicine, Northwestern University Medical School, 240 East Huron Avenue, Chicago, IL 60611, USA.

  ₄₁Flavell, Richard A, ₁₃Thompson, Craig B, ₁₉Strasser, Andreas, ₁Brunelle, Joslyn K, ₃Shroff, Emelyn H, ₄Perlman, Harris, ₄Danial, Nika N, ₄Keith, Brian, ₁₄Chandel, Navdeep S, ₈Moraes, Carlos T.

• IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells. (2007) >>

  Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

  ₁Eynon, Elizabeth E, ₄Homer, Robert, ₄₁Flavell, Richard A, ₁Temann, Ulla-Angela, ₁Laouar, Yasmina.

• Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury. (2007) >>

  Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas 77030, USA.

  ₂Vallejo, Jesus G, ₁₀Yang, Zhao, ₁₁Huang, Chien-Hua, ₇₉Li, Na, ₄₁Flavell, Richard A, ₂Baker, J Scott, ₂Purevjav, Enkhsaikhan, ₁Hardarson, Hordur S, ₃Bowles, Neil E, ₅Alexopoulou, Lena.

• Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis. (2007) >>

  Institute for Cancer Research and Treatment, University of Torino Medical School, Division of Molecular Oncology, Candiolo, Turin, Italy.

  ₄Maina, Flavio, ₂Fazzari, Pietro, ₂Gianola, Sara, ₄Rossi, Ferdinando, ₁Sottile, Antonino, ₄₁Flavell, Richard A, ₂Comoglio, Paolo Maria, ₅Alexopoulou, Lena, ₄Tamagnone, Luca, ₃Eickholt, Britta J, ₁Penachioni, Junia.