₄₁Frank J Gonzalez

Frank J Gonzalez Articles (41) [selected PubMed articles for the year 2007 with the links to a full text at PubMed]

• Too much data, only first 100 publications and/or coauthors will be displayed. Unabridged data can only be viewed as XML or CSV documents.

• Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

  ₄₁Gonzalez, Frank J, ₆Kliewer, Steven A, ₉Kim, Insook, ₄Ito, Shinji, ₆Inagaki, Takeshi, ₄Guo, Grace L, ₄Choi, Mihwa, ₁Ahn, Sung-Hoon.

• Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines. (2007) >>

  Department of Veterinary and Biomedical Sciences and the Center of Molecular Toxicology and Carcinogenesis, Pennsylvania State University, University Park, PA 16802, USA.

  ₁Killins, Renee L, ₄₁Gonzalez, Frank J, ₁Borland, Michael G, ₈Billin, Andrew N, ₂Hollingshead, Holly E, ₂Girroir, Elizabeth E, ₁₄Amin, Shantu, ₁₁Willson, Timothy M, ₆Sharma, Arun K, ₁₁Peters, Jeffrey M.

• Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo. (2007) >>

  Department of Pathology, Osaka City University Medical School, Osaka, Japan.

  ₁₀Morimura, Keiichirou, ₁₁Fukushima, Shoji, ₄₁Gonzalez, Frank J, ₃Kang, Jin Seok, ₈Wanibuchi, Hideki.

• PPARalpha protects proximal tubular cells from acute fatty acid toxicity. (2007) >>

  Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University School of Medicine, Matsumoto, Japan.

  ₆Kamijo, Yuji, ₄₁Gonzalez, Frank J, ₁₀Higuchi, Makoto, ₈Takahashi, Kyoko, ₄Hora, Kazuhiko, ₃Shigematsu, Hidekazu, ₁₅Kiyosawa, Kendo, ₂Kono, Keiichi, ₆Aoyama, Toshifumi, ₃Ehara, Takashi.

• Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation. (2007) >>

  Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

  ₂₅Sugiyama, Yuichi, ₁Kikuchi, Ryota, ₄₁Gonzalez, Frank J, ₉Kim, Insook, ₆Hattori, Naka, ₁₈Kusuhara, Hiroyuki, ₈Shiota, Kunio.

• PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism. (2007) >>

  Department of Veterinary and Biomedical Sciences , The Pennsylvania State University, 312 Life Sciences Building, University Park, Pennsylvania 16802, USA.

  ₁₀Morimura, Keiichirou, ₄₁Gonzalez, Frank J, ₁Adachi, Masahiro, ₈Billin, Andrew N, ₂Hollingshead, Holly E, ₂Kennett, Mary J, ₁₁Willson, Timothy M, ₁₁Peters, Jeffrey M.

• Metabolomics. (2007) >>

  Institute of Pharmacology, 1st Faculty of Medicine, Charles University, 128 00 Praha 2, Czech Republic.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J.

• Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice. (2007) >>

  Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA.

  ₄₁Gonzalez, Frank J, ₁Kuriakose, George, ₅Shah, Yatrik M, ₂Thorp, Edward, ₉Tabas, Ira.

• ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output. (2007) >>

  Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan.

  ₆Miyata, Masaaki, ₄₁Gonzalez, Frank J, ₆Nomoto, Masahiro, ₂Kurosawa, Tohru, ₂Shibasaki, Shigeki, ₁Shindo, Yasuhiro, ₈Yamazoe, Yasushi, ₄Yoshinari, Kouichi, ₁Shimada, Miki.

• CCAAT/enhancer-binding protein delta (C/EBPdelta) maintains amelogenin expression in the absence of C/EBPalpha in vivo. (2007) >>

  The Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, California 90033, USA.

  ₄₁Gonzalez, Frank J, ₆Snead, Malcolm L, ₂Zhou, Yan Larry, ₂Xu, Yucheng.

• Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR. (2007) >>

  Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi 466-8550, Japan.

  ₄₁Gonzalez, Frank J, ₆Lee, Chul-Ho, ₈Ito, Yuki, ₁₃Nakajima, Tamie, ₇Yamanoshita, Osamu, ₃Zhang, Shu-yun, ₂Yanagiba, Yukie, ₁₀Kamijima, Michihiro, ₇Kim, Heon.

• Differential effects of aging, drinking and exercise on serum cholesterol levels dependent on the PPARA-V227A polymorphism. (2007) >>

  Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Japan.

  ₄₁Gonzalez, Frank J, ₂Nakahara, Ai, ₃Naito, Hisao, ₁₂Katoh, Takahiko, ₆Tanaka, Naoki, ₁₃Nakajima, Tamie, ₇Yamanoshita, Osamu, ₆Aoyama, Toshifumi, ₁₀Kamijima, Michihiro.

• Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₁Zhen, Yueying, ₇Chen, Chi, ₆Krausz, Kristopher W.

• The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter. (2007) >>

  Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska University Hospital at Huddinge, Stockholm, Sweden.

  ₄₁Gonzalez, Frank J, ₁Dongol, Bikesh, ₉Kim, Insook, ₃Shah, Yatrik, ₄Hunt, Mary C.

• Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice. (2007) >>

  Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire, USA.

  ₄₁Gonzalez, Frank J, ₄Sinclair, Jacqueline F, ₁Walton-Strong, Brooke W, ₃Szakacs, Juliana G, ₅Jeffery, Elizabeth H, ₆Greenblatt, David J, ₆Court, Michael H, ₂Hunt, Jane A, ₁Kostrubsky, Vsevolod, ₄Sinclair, Peter R, ₄Gorman, Nadia, ₁Allard, Jenna L, ₃Wrighton, Steven A, ₁Duan, Su X, ₂Hao, Qin, ₁Wolf, Kristina K, ₁Wood, Sheryl G, ₂Von Moltke, Lisa L.

• Dietary phytochemicals regulate whole-body CYP1A1 expression through an arylhydrocarbon receptor nuclear translocator-dependent system in gut. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

  ₄₁Gonzalez, Frank J, ₁Satoh, Junko, ₁Yim, SunHee, ₄Ito, Shinji, ₇Chen, Chi.

• Rifaximin is a gut-specific human pregnane X receptor activator. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bldg. 37, Room 3106, Bethesda, MD 20892, USA.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₅Ma, Xiaochao, ₆Krausz, Kristopher W, ₅Shah, Yatrik M, ₄Guo, Grace L, ₃₈Wang, Ting.

• A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. (2007) >>

  Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurimamachiya-cho, Tsu 514-8507, Japan.

  ₄₁Gonzalez, Frank J, ₁₉Yamada, Yoshiji, ₃₆Murohara, Toyoaki, ₁₃Nakajima, Tamie, ₈Ichihara, Sahoko, ₁₀₄Li, Ping, ₁₁Kondo, Takahisa, ₇Ichihara, Gaku.

• Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. (2007) >>

  Department of Medicine, Division of Endocrinology and Metabolism, UCSD, La Jolla, California, USA.

  ₁Bandyopadyhay, Gautam, ₁₂Olefsky, Jerrold M, ₄₁Gonzalez, Frank J, ₂Benner, Chris, ₁₅Glass, Christopher K, ₂Reichart, Donna, ₈Febbraio, Mark A, ₃Nguyen, M T Audrey, ₂Nguyen, Anh-Khoi, ₂Leung, Ho-Yin, ₆Watt, Matthew J, ₁₄Subramaniam, Shankar, ₄Hevener, Andrea L, ₃Ricote, Mercedes, ₁Folian, Brian.

• Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. (2007) >>

  National Cancer Institute, Bethesda, MD 20892, USA.

  ₁₀Morimura, Keiichirou, ₄₁Gonzalez, Frank J, ₅Shah, Yatrik M, ₂₀Yang, Qian, ₁Tanabe, Tomotaka, ₂Takagi, Mitsuhiro.

• Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate Cytochrome P450 2a5 transcription through a common E-box site. (2007) >>

  Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland.

  ₂Lämsä, Virpi, ₄₁Gonzalez, Frank J, ₂Arpiainen, Satu, ₅Hakkola, Jukka, ₁Yim, Sun Hee, ₇Pelkonen, Olavi.

• Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. (2007) >>

  Department of Veterinary and Biomedical Sciences and The Center for Molecular Toxicology and Carcinogenesis, The Huck Institute of Life Sciences, The Pennsylvania State University, University Park 16802, United States.

  ₄₁Gonzalez, Frank J, ₈Billin, Andrew N, ₂Burdick, Andrew D, ₂Girroir, Elizabeth E, ₁₁Willson, Timothy M, ₁₁Peters, Jeffrey M, ₁Bility, Moses T.

• Glucocorticoid signaling synchronizes the liver circadian transcriptome. (2007) >>

  MRC Laboratory of Molecular Biology, Hills Road, Cambridge, Cabridgeshire, UK.

  ₄₁Gonzalez, Frank J, ₄Karp, Natasha A, ₈Maywood, Elizabeth S, ₁₄Lilley, Kathryn S, ₁King, Verdun M, ₁₀Inoue, Yusuke, ₂Reddy, Akhilesh B, ₈Kyriacou, Charalambos P, ₇Hastings, Michael H.

• Animal models for human risk assessment: the peroxisome proliferator-activated receptor alpha-humanized mouse. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₄₁Gonzalez, Frank J.

• Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development. (2007) >>

  Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611-3008, USA.

  ₁Karpus, William, ₁Kashireddy, Papreddy V, ₄₁Gonzalez, Frank J, ₄Rao, M Sambasiva, ₄Jia, Yuzhi, ₅Sarkar, Joy, ₇Reddy, Janardan K, ₃Ahmed, Mohamed R, ₄Yu, Songtao, ₃Viswakarma, Navin, ₉Matsumoto, Kojiro.

• Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8. (2007) >>

  Laboratory of Systems Biology and Medicine, Research Center for Advanced Science and Technology, University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo, Japan.

  ₂₁Kodama, Tatsuhiko, ₄₁Gonzalez, Frank J, ₃Osborne, Timothy F, ₂Urashima, Yasuyo, ₉Kim, Insook, ₆Hasegawa, Go, ₁Magoori, Kenta, ₉Tanaka, Toshiya, ₁Daigo, Kenji, ₅Ohashi, Riuko, ₁Kojima, Noriaki, ₄Jiang, Shuying, ₂Maejima, Takashi, ₂Uchida, Aoi, ₁Kudo, Hiromi, ₆Sakai, Juro, ₁Sumi, Koichi, ₁Ohguchi, Hiroto, ₁Sakakibara, Iori, ₈Naito, Makoto, ₉Hamakubo, Takao, ₉Okamura, Masashi.

• Hepatocyte-restricted constitutive activation of PPAR alpha induces hepatoproliferation but not hepatocarcinogenesis. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₄₁Gonzalez, Frank J, ₄Ito, Shinji, ₂₀Yang, Qian.

• Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway. (2007) >>

  Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

  ₄₁Gonzalez, Frank J, ₁Asaeda, Nobuyuki, ₂Tagawa, Yoshiaki, ₆Lee, Chul-Ho, ₈Ito, Yuki, ₁₃Nakajima, Tamie, ₇Yamanoshita, Osamu, ₆Aoyama, Toshifumi, ₃Furuhashi, Koichi, ₁₀Kamijima, Michihiro, ₇Ichihara, Gaku.

• Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₁₀Morimura, Keiichirou, ₄₁Gonzalez, Frank J, ₉Kim, Insook, ₁₀Ward, Jerrold M, ₃Shah, Yatrik, ₂₀Yang, Qian.

• Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression. (2007) >>

  Laboratory of Metabolism, Center of Cancer Research, National Cancer Institute, National Institutes of health, Bldg. 37, Rm. 3106, Bethesda, MD 20892, USA.

  ₁₀Morimura, Keiichirou, ₄₁Gonzalez, Frank J, ₉Kim, Insook, ₅Ma, Xiaochao, ₅Shah, Yatrik M.

• A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₃Malfatti, Michael A, ₅Ma, Xiaochao, ₄Kimura, Shioko, ₇Chen, Chi, ₆Krausz, Kristopher W, ₄Felton, James S.

• Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality. (2007) >>

  Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

  ₂Ivashchenko, Christine Y, ₄₁Gonzalez, Frank J, ₁Duquaine, Damon C, ₄D'Alecy, Louis G, ₈Vinson, Charles, ₃Brosius, Frank C, ₃Duan, Sheng Zhong, ₁Pierre, Melissa A, ₃Mortensen, Richard M, ₂Milstone, David S, ₃Whitesall, Steven E.

• Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD 20892, USA.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₃Malfatti, Michael A, ₅Ma, Xiaochao, ₆Krausz, Kristopher W, ₄Felton, James S, ₃Chen, Chong-Sheng, ₆Nebert, Daniel W, ₈Waxman, David J.

• The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₁Giri, Sarbani, ₆Krausz, Kristopher W.

• The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

  ₉Idle, Jeffrey R, ₁₀Feigenbaum, Lionel, ₄₁Gonzalez, Frank J, ₅Ma, Xiaochao, ₁Cheung, Connie, ₆Krausz, Kristopher W, ₄Guo, Grace L, ₃Shah, Yatrik.

• Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

  ₁₀Morimura, Keiichirou, ₄₁Gonzalez, Frank J, ₅Shah, Yatrik M.

• The 2006 Bernard B. Brodie Award Lecture. Cyp2e1. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Building 37/Room 3106, Bethesda, MD 20892, USA.

  ₄₁Gonzalez, Frank J.

• Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate. (2007) >>

  Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.

  ₆Kamijo, Yuji, ₄₁Gonzalez, Frank J, ₁₀Higuchi, Makoto, ₈Takahashi, Kyoko, ₄Hora, Kazuhiko, ₈Ito, Yuki, ₃Shigematsu, Hidekazu, ₁₅Kiyosawa, Kendo, ₁₃Nakajima, Tamie, ₂Kono, Keiichi, ₆Aoyama, Toshifumi.

• Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl)ethane. (2007) >>

  Toxicology Section, Centro Investigación y Estudios Avazados, Mexico City, D.F. 07000, Mexico.

  ₁Medina-Díaz, Irma M, ₄₁Gonzalez, Frank J, ₁Arteaga-Illán, Georgina, ₃Elizondo, Guillermo, ₂Vega, Libia, ₂de León, Mario Bermúdez, ₂Cisneros, Bulmaro, ₂Sierra-Santoyo, Adolfo.

• CYP3A4 and pregnane X receptor humanized mice. (2007) >>

  Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

  ₄₁Gonzalez, Frank J.

• LC-MS-based metabolomics in drug metabolism. (2007) >>

  Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

  ₉Idle, Jeffrey R, ₄₁Gonzalez, Frank J, ₇Chen, Chi.